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American Journal of Clinical Nutrition, Vol 38, 20-31, Copyright © 1983 by The American Society for Clinical Nutrition, Inc

ORIGINAL RESEARCH COMMUNICATIONS

A high protein, low calorie liquid diet in the treatment of very obese adolescents: long-term effect on lean body mass

MR Brown, WJ Klish, J Hollander, MA Campbell and GB Forbes

The use of Optifast-70, a high protein liquid diet, when used in the range of 500 to 700 cal over 5 months in very obese adolescents, was associated with weight loss of 20 to 25% of initial weight of which 70 to 75% of the loss was due to fat. No significant side effects were noted. Twenty-four hour electrocardiographic monitoring showed no significant changes, and linear growth continued. Lean body mass loss was 36% of the weight lost during the first 5 wks, but was only 10% of the weight lost during the next few months. Two adolescent males had negative phosphorus and nitrogen balances over the first 4 wk, implying that males may have slightly higher phosphorus, nitrogen, and calorie requirements.


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