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American Journal of Clinical Nutrition, Vol 40, 153-158, Copyright © 1984 by The American Society for Clinical Nutrition, Inc

ORIGINAL RESEARCH COMMUNICATIONS

Five-day comparison of the doubly labeled water method with respiratory gas exchange

DA Schoeller and P Webb

Previous studies have indicated that the doubly labeled water method can be used to measure energy expenditure in free-living humans. In this study, we compare the doubly labeled water method with nearly continuous respiratory gas exchange in five healthy adults. Total body water and isotope elimination rates were determined by mass spectrometric analysis of urinary water after the administration of 2H2 18O. Respiratory gas exchange was measured 22 to 23 h/day for 5 consecutive days. Energy expenditures from the doubly labeled water method averaged 6% more than those from respiratory gas exchange with an 8% coefficient of variation.


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L. de Jonge, J. P DeLany, T. Nguyen, J. Howard, E. C Hadley, L. M Redman, and E. Ravussin
Validation study of energy expenditure and intake during calorie restriction using doubly labeled water and changes in body composition
Am. J. Clinical Nutrition, January 1, 2007; 85(1): 73 - 79.
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Copyright © 1984 by The American Society for Nutrition