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American Journal of Clinical Nutrition, Vol 40, 260-269, Copyright © 1984 by The American Society for Clinical Nutrition, Inc


ORIGINAL RESEARCH COMMUNICATIONS

Total body water and total body potassium in anorexia nervosa

DT Dempsey, LO Crosby, E Lusk, JL Oberlander, MJ Pertschuk and JL Mullen

In the ill hospitalized patient with clinically relevant malnutrition, there is a measurable decrease in the ratio of the total body potassium to total body water (TBK/TBW) and a detectable increase in the ratio of total exchangeable sodium to total exchangeable potassium (Nae/Ke). To evaluate body composition analyses in anorexia nervosa patients with chronic uncomplicated semistarvation, TBK and TBW were measured by whole body K40 counting and deuterium oxide dilution in 10 females with stable anorexia nervosa and 10 age-matched female controls. The ratio of TBK/TBW was significantly (p less than 0.05) higher in anorexia nervosa patients than controls. The close inverse correlation found in published studies between TBK/TBW and Nae/Ke together with our results suggest that in anorexia nervosa, Nae/Ke may be low or normal. A decreased TBK/TBW is not a good indicator of malnutrition in the anorexia nervosa patient. The use of a decreased TBK/TBW ratio or an elevated Nae/Ke ratio as a definition of malnutrition may result in inappropriate nutritional management in the patient with severe nonstressed chronic semistarvation.


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JPEN J Parenter Enteral NutrHome page
A. Piccoli, M. Codognotto, L. Di Pascoli, G. Boffo, and L. Caregaro
Body Mass Index and Agreement Between Bioimpedance and Anthropometry Estimates of Body Compartments in Anorexia Nervosa
JPEN J Parenter Enteral Nutr, May 1, 2005; 29(3): 148 - 156.
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