AJCN Tufts Nutrition Symposium, Boston Sept 24-26
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

This Article
Right arrow Full Text (PDF)
Right arrow Purchase Article
Right arrow View Shopping Cart
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Markowitz, M. E.
Right arrow Articles by Mizruchi, M.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Markowitz, M. E.
Right arrow Articles by Mizruchi, M.
Agricola
Right arrow Articles by Markowitz, M. E.
Right arrow Articles by Mizruchi, M.

American Journal of Clinical Nutrition, Vol 41, 689-696, Copyright © 1985 by The American Society for Clinical Nutrition, Inc

ORIGINAL RESEARCH COMMUNICATIONS

Circadian variations in serum zinc (Zn) concentrations: correlation with blood ionized calcium, serum total calcium and phosphate in humans

ME Markowitz, JF Rosen and M Mizruchi

Serum zinc (Zn) concentrations were determined in sequentially drawn blood samples from six healthy adult males. Each subject had blood sampling performed every 30 minutes for 24 hours. Mean Zn concentrations at each time point (n = 6, 48 time points) were plotted and fitted by a polynomial regression of the data against time. A "U" shaped curve was derived; we found peak Zn levels at 9:30 AM, a midtrough at 8 PM and a peak-trough difference of 19 micrograms/dl. Correlation with a similarly derived 24-h ionized calcium pattern was strikingly high, r = .923, p less than .001. An intermediate correlation between the Zn and phosphate patterns was observed, r = - .493, p less than .01; and no significant correlation occurred between Zn and total calcium rhythms, r = .167. These data conclusively demonstrate the presence of a circadian rhythm in serum Zn in healthy adult males. Furthermore, the high correlation between the Zn and ionized calcium patterns suggests a common regulator.


This article has been cited by other articles:


Home page
 Am. J. Clin. Nutr.Home page
T. A Strand, R. K Adhikari, R. K Chandyo, P. R Sharma, and H. Sommerfelt
Predictors of plasma zinc concentrations in children with acute diarrhea
Am. J. Clinical Nutrition, March 1, 2004; 79(3): 451 - 456.
[Abstract] [Full Text] [PDF]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Copyright © 1985 by The American Society for Nutrition