American Journal of Clinical Nutrition, Vol 42, 1206-1220, Copyright © 1985 by The American Society for Clinical Nutrition, Inc

ORIGINAL RESEARCH COMMUNICATIONS

Relationship of diet to the fatty acid composition of human adipose tissue structural and stored lipids

CJ Field, A Angel and MT Clandinin

The habitual intake of 20 healthy free-living subjects was determined by two 7-day food records. Documented fatty acid intakes were utilized to examine the influence of fatty acid intake on fatty acid composition of stored and structural lipids in subcutaneous adipose tissue. Subjects with higher intakes of saturated fatty acids exhibited increased levels of total saturated fatty acids and decreased polyunsaturated fatty acids in adipose tissue triglycerides (p less than 0.01). The dietary P/S ratio was significantly related to the saturated and polyunsaturated content of stored lipids. In the phospholipid fraction, relationships were found between dietary C18:2(6) and the P/S ratio of phosphatidylcholine (p less than 0.05). The essential fatty acid content of the two phospholipids studied was related to the dietary fats consumed. Relationships were identified between major fatty acids in the triglyceride and phospholipid fraction. Although diet was found to relate to fatty acid composition, the structural lipids in human adipose tissue appear more resistant to compositional change than stored triglycerides.

This article has been cited by other articles:

				H. J. Murff, X.-O. Shu, H. Li, Q. Dai, A. Kallianpur, G. Yang, H. Cai, W. Wen, Y.-T. Gao, and W. Zheng A Prospective Study of Dietary Polyunsaturated Fatty Acids and Colorectal Cancer Risk in Chinese Women Cancer Epidemiol. Biomarkers Prev., August 1, 2009; 18(8): 2283 - 2291. [Abstract] [Full Text] [PDF]

				J. Ren, I. Dimitrov, A. D. Sherry, and C. R. Malloy Composition of adipose tissue and marrow fat in humans by 1H NMR at 7 Tesla J. Lipid Res., September 1, 2008; 49(9): 2055 - 2062. [Abstract] [Full Text] [PDF]

				A. Baylin, M. K. Kim, A. Donovan-Palmer, X. Siles, L. Dougherty, P. Tocco, and H. Campos Fasting Whole Blood as a Biomarker of Essential Fatty Acid Intake in Epidemiologic Studies: Comparison with Adipose Tissue and Plasma Am. J. Epidemiol., August 15, 2005; 162(4): 373 - 381. [Abstract] [Full Text] [PDF]

				M. Garaulet, F. Perez-Llamas, M. Perez-Ayala, P. Martinez, F. S. de Medina, F. J Tebar, and S. Zamora Site-specific differences in the fatty acid composition of abdominal adipose tissue in an obese population from a Mediterranean area: relation with dietary fatty acids, plasma lipid profile, serum insulin, and central obesity Am. J. Clinical Nutrition, November 1, 2001; 74(5): 585 - 591. [Abstract] [Full Text] [PDF]

				S. C Cunnane, R. Ross, J. L Bannister, and D. J. Jenkins {beta}-Oxidation of linoleate in obese men undergoing weight loss Am. J. Clinical Nutrition, April 1, 2001; 73(4): 709 - 714. [Abstract] [Full Text] [PDF]

				V. L Freeman, M. Meydani, S. Yong, J. Pyle, R. Durazo-Arvizu, Y. Liao, R. C Flanigan, and W B. Waters Assessing the effect of fatty acids on prostate carcinogenesis in humans: does self-reported dietary intake rank prostatic exposure correctly? Am. J. Clinical Nutrition, April 1, 2001; 73(4): 815 - 820. [Abstract] [Full Text] [PDF]

				L. K. Summers, S. C Barnes, B. A Fielding, C. Beysen, V. Ilic, S. M Humphreys, and K. N Frayn Uptake of individual fatty acids into adipose tissue in relation to their presence in the diet Am. J. Clinical Nutrition, June 1, 2000; 71(6): 1470 - 1477. [Abstract] [Full Text] [PDF]

				E. Guallar, A. Aro, F. J. Jimenez, J. M. Martin-Moreno, I. Salminen, P. van't Veer, A. F. M. Kardinaal, J. Gomez-Aracena, B. C. Martin, L. Kohlmeier, et al. Omega-3 Fatty Acids in Adipose Tissue and Risk of Myocardial Infarction : The EURAMIC Study Arterioscler Thromb Vasc Biol, April 1, 1999; 19(4): 1111 - 1118. [Abstract] [Full Text] [PDF]