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American Journal of Clinical Nutrition, Vol 44, 519-551, Copyright © 1986 by The American Society for Clinical Nutrition, Inc

REVIEW ARTICLES

The toxic impact of parenteral solutions on the metabolism of cells: a hypothesis for physiological parenteral therapy

RL Veech

The prescribing of parenteral fluids has become so routine that most physicians have become oblivious to the toxic impact of current practices on the cellular metabolism of their patients. Few physicians recognize the iatrogenic threat of replacement of body fluids based solely on concepts of volumetric and caloric need. Understanding the metabolic and ionic organization of cells can provide the physician means to use parenteral fluids to control the inherent metabolic energy of cells. Application of new insight into physical chemistry and metabolic properties of the cell can enhance the physician's therapy of the critically ill patient.


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Copyright © 1986 by The American Society for Nutrition