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American Journal of Clinical Nutrition, Vol 45, 476-483, Copyright © 1987 by The American Society for Clinical Nutrition, Inc

ORIGINAL RESEARCH COMMUNICATIONS

Subnormal concentrations of serum selenium and plasma carnitine in chronically tube-fed patients

AG Feller, D Rudman, PR Erve, RC Johnson, J Boswell, DL Jackson and DE Mattson

Forty-seven tube-fed nursing home patients were investigated with regard to serum or plasma selenium (Se), carnitine, and red blood cell (RBC) glutathione peroxidase (GSH-Px). Thirty-six patients were tube fed with Isocal, and 11 were tube fed with Compleat B, an L-carnitine- containing formula. Eighteen elderly nursing home patients and 10 young adults served as controls. Serum Se and plasma carnitine were lowest (p less than 0.05) in the Isocal patients. In all 36 Isocal subjects, Se was below normal, and in 26% of Isocal patients RBC GSH-Px was also below normal. Free and total carnitine were below normal in most Isocal subjects. All 11 Compleat B patients had subnormal serum Se, but most had normal carnitine concentrations. These data suggest that enteral formulae in nursing homes should contain greater than 100 micrograms Se and on the order of a mmol carnitine/1600 kcal.


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B. Duncan, L. L. Barton, J. Lloyd, and M. Marks-Katz
Dietary Considerations in Osteopenia in Tube-Fed Nonambulatory Children with Cerebral Palsy
Clinical Pediatrics, April 1, 1999; 38(3): 133 - 137.
[Abstract] [PDF]


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Copyright © 1987 by The American Society for Nutrition