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American Journal of Clinical Nutrition, Vol 45, 617-624, Copyright © 1987 by The American Society for Clinical Nutrition, Inc

ORIGINAL RESEARCH COMMUNICATIONS

Distribution of selenium in human milk

JA Milner, L Sherman and MF Picciano

The present studies were designed to characterize selenium distribution in human milk. These studies reveal that most selenium in human milk is protein bound. Percentage dialyzable selenium varied proportionally with total selenium content of milk but not with stage of lactation. Neither rate of freezing nor frozen storage of samples for one month influenced distribution profiles. At least nine selenoproteins were detected in dialyzed milk samples following molecular sieve (Sephadex) chromatography. Glutathione peroxidase accounted for approximately 15- 30% of selenium found in milk. Approximately half of peroxidase activity in human milk was associated with selenium dependent glutathione peroxidase activity.


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L. Daniels, R. A Gibson, K. Simmer, P. Van Dael, and M. Makrides
Selenium status of term infants fed selenium-supplemented formula in a randomized dose-response trial
Am. J. Clinical Nutrition, July 1, 2008; 88(1): 70 - 76.
[Abstract] [Full Text] [PDF]


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Copyright © 1987 by The American Society for Nutrition