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American Journal of Clinical Nutrition, Vol 46, 353-359, Copyright © 1987 by The American Society for Clinical Nutrition, Inc

ORIGINAL RESEARCH COMMUNICATIONS

Metabolic balance studies for zinc and copper in housebound elderly people and the relationship between zinc balance and leukocyte zinc concentrations

VW Bunker, LJ Hinks, MF Stansfield, MS Lawson and BE Clayton

Five-day metabolic balance studies for zinc and copper were carried out in 20 housebound elderly people with stable chronic diseases. Subjects were age 70.0-85.1 y, lived in their own homes, and ate self-selected diets. Mean daily intakes for Zn and Cu were 90 mumol and 13.4 mumol with mean negative balances of -16 and -1.1 mumol, respectively. Both balance values significantly differed from equilibrium (p less than 0.05). For Zn and Cu, respectively, mean concentrations were 11.3 and 22.1 mumol/L plasma, 103 and 19.4 mumol/L whole blood, and 98 and 8.7 pmol/10(6) leukocytes. The results for Zn and Cu balance and leukocyte concentrations were different from those obtained by us for healthy elderly people (Am J Clin Nutr 1984;40: 1096-120). A highly significant (r = 0.75, p less than 0.001) correlation was observed between zinc balance and leukocyte zinc concentrations.


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Copyright © 1987 by The American Society for Nutrition