AJCN Tufts Nutrition Symposium, Boston Sept 24-26
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American Journal of Clinical Nutrition, Vol 46, 772-777, Copyright © 1987 by The American Society for Clinical Nutrition, Inc

ORIGINAL RESEARCH COMMUNICATIONS

Rise in plasma trimethyllysine levels in humans after oral lysine load

C Vijayasarathy, L Khan-Siddiqui, SN Murthy and MS Bamji
Department of Biochemistry, Indian Council of Medical Research, Hyderabad.

Oral administration of 5 g of lysine to healthy male volunteers produced a marked and progressive rise in plasma trimethyllysine (TML) from 3 to 24 h after the lysine load. Urinary TML did not register a similar rise. Plasma and urinary carnitine also increased after the lysine load. A similar rise in TML or carnitine was not seen after a 5 g tryptophan load. This suggests that the effect is specific for lysine and is not a nonspecific consequence of amino acid load.




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Copyright © 1987 by The American Society for Nutrition