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American Journal of Clinical Nutrition, Vol 49, 404-408, Copyright © 1989 by The American Society for Clinical Nutrition, Inc


ORIGINAL RESEARCH COMMUNICATIONS

Measured and predicted calorie requirements of adults during recovery from severe burn trauma

JJ Cunningham, MT Hegarty, PA Meara and JF Burke
Pediatric Endocrine Unit, Shriners Burns Institute, Children's Service, Boston, MA 02114.

Major burn trauma produces large elevations in metabolic energy expenditure (MEE) during acute care. However, overfeeding can occur and is detrimental to recovery. The formulae often used to estimate caloric support to meet MEE are based on body weight, predicted resting metabolic rate (RMR), body surface area, or the total body surface area burned (BSAB). These predictive equations originate from studies of less than or equal to 30 patients generally lacking measurements beyond the third week of convalescence. We report 565 measurements by indirect calorimetry for 122 adults between the burn day and day 149 postburn. A standardized protocol of nutritional support and early wound closure was followed. Predictions of MEE are compared in subcategories of BSAB (2-25%; 30-50%; 51-75%; and 76-98%). For major burns exceeding 30% BSAB, 2X the predicted RMR was consistently closest to the measured MEE, assuring adequate calorie provision while minimizing the risk of overfeeding.


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Physiol. GenomicsHome page
M. Vemula, F. Berthiaume, A. Jayaraman, and M. L. Yarmush
Expression profiling analysis of the metabolic and inflammatory changes following burn injury in rats
Physiol Genomics, June 17, 2004; 18(1): 87 - 98.
[Abstract] [Full Text] [PDF]


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J. Nutr.Home page
D. A. De-Souza and L. J. Greene
Pharmacological Nutrition After Burn Injury
J. Nutr., May 1, 1998; 128(5): 797 - 803.
[Abstract] [Full Text]




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