| HOME | HELP | FEEDBACK | SUBSCRIPTIONS | ARCHIVE | SEARCH | TABLE OF CONTENTS |
|
|
|
|||||||
|
|||||||||
American Journal of Clinical Nutrition, Vol 49, 1274-1282, Copyright © 1989 by The American Society for Clinical Nutrition, Inc
ORIGINAL RESEARCH COMMUNICATIONS |
RF Hurrell, DE Furniss, J Burri, P Whittaker, SR Lynch and JD Cook
Nestle Research Center, Nestec Ltd, Vers-chez-les-Blanc, Lausanne, Switzerland.
Hemoglobin-repletion tests in rats, organoleptic studies, and iron- absorption studies in humans were used to search for Fe sources with high bioavailability that could be added to infant cereals as alternatives to the Fe compounds currently used for fortification. From rat and organoleptic studies on 11 alternative Fe sources, ferrous fumarate, ferrous succinate, and ferric saccharate were selected as the most suitable for infant-cereal fortification and, by use of radioactive labels, absorption of those compounds from fortified cereal was measured in adult human volunteers. There was no difference in absorption between ferrous fumarate and ferrous sulfate whereas the values for ferrous succinate, ferrous saccharate (10% Fe), and ferric pyrophosphate were 92%, 74%, and 39% of the ferrous sulfate values, respectively. We conclude that ferrous fumarate and ferrous succinate are highly available Fe sources in man that can be used to fortify infant cereals without causing fat oxidation or discoloration.
This article has been cited by other articles:
|
|
 |
|
  D. Moretti, M. B Zimmermann, R. Wegmuller, T. Walczyk, C. Zeder, and R. F Hurrell Iron status and food matrix strongly affect the relative bioavailability of ferric pyrophosphate in humans Am. J. Clinical Nutrition, March 1, 2006; 83(3): 632 - 638. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 M. Hernandez, V. Sousa, S. Villalpando, A. Moreno, I. Montalvo, and M. Lopez-Alarcon Cooking and fe fortification have different effects on fe bioavailability of bread and tortillas. J. Am. Coll. Nutr., February 1, 2006; 25(1): 20 - 25. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
M. B Zimmermann, P. Winichagoon, S. Gowachirapant, S. Y Hess, M. Harrington, V. Chavasit, S. R Lynch, and R. F Hurrell Comparison of the efficacy of wheat-based snacks fortified with ferrous sulfate, electrolytic iron, or hydrogen-reduced elemental iron: randomized, double-blind, controlled trial in Thai women Am. J. Clinical Nutrition, December 1, 2005; 82(6): 1276 - 1282. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 S. J. Fomon, S. E. Nelson, R. E. Serfass, and E. E. Ziegler Absorption and Loss of Iron in Toddlers Are Highly Correlated J. Nutr., April 1, 2005; 135(4): 771 - 777. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
L. Davidsson, E. Ziegler, C. Zeder, T. Walczyk, and R. Hurrell Sodium iron EDTA [NaFe(III)EDTA] as a food fortificant: erythrocyte incorporation of iron and apparent absorption of zinc, copper, calcium, and magnesium from a complementary food based on wheat and soy in healthy infants Am. J. Clinical Nutrition, January 1, 2005; 81(1): 104 - 109. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
R. Wegmuller, M. B. Zimmermann, D. Moretti, M. Arnold, W. Langhans, and R. F. Hurrell Particle Size Reduction and Encapsulation Affect the Bioavailability of Ferric Pyrophosphate in Rats J. Nutr., December 1, 2004; 134(12): 3301 - 3304. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
M. B Zimmermann, R. Wegmueller, C. Zeder, N. Chaouki, R. Biebinger, R. F Hurrell, and E. Windhab Triple fortification of salt with microcapsules of iodine, iron, and vitamin A Am. J. Clinical Nutrition, November 1, 2004; 80(5): 1283 - 1290. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
S. A Sarker, L. Davidsson, H. Mahmud, T. Walczyk, R. F Hurrell, N. Gyr, and G. J Fuchs Helicobacter pylori infection, iron absorption, and gastric acid secretion in Bangladeshi children Am. J. Clinical Nutrition, July 1, 2004; 80(1): 149 - 153. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
J. H. Swain, S. M. Newman, and J. R. Hunt Bioavailability of Elemental Iron Powders to Rats Is Less than Bakery-Grade Ferrous Sulfate and Predicted by Iron Solubility and Particle Surface Area J. Nutr., November 1, 2003; 133(11): 3546 - 3552. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
M. B Zimmermann, C. Zeder, N. Chaouki, A. Saad, T. Torresani, and R. F Hurrell Dual fortification of salt with iodine and microencapsulated iron: a randomized, double-blind, controlled trial in Moroccan schoolchildren Am. J. Clinical Nutrition, February 1, 2003; 77(2): 425 - 432. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
T. Walczyk, L. Davidsson, L. Rossander-Hulthen, L. Hallberg, and R. F Hurrell No enhancing effect of vitamin A on iron absorption in humans Am. J. Clinical Nutrition, January 1, 2003; 77(1): 144 - 149. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
M. Hernandez, V. Sousa, A. Moreno, S. Villapando, and M. Lopez-Alarcon Iron Bioavailability and Utilization in Rats Are Lower from Lime-Treated Corn Flour than from Wheat Flour When They Are Fortified with Different Sources of Iron J. Nutr., January 1, 2003; 133(1): 154 - 159. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
R. F. Hurrell Fortification: Overcoming Technical and Practical Barriers J. Nutr., April 1, 2002; 132(4): 806S - 812. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
L. Davidsson, T. Dimitriou, E. Boy, T. Walczyk, and R. F Hurrell Iron bioavailability from iron-fortified Guatemalan meals based on corn tortillas and black bean paste Am. J. Clinical Nutrition, March 1, 2002; 75(3): 535 - 539. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
S. J. Fomon Infant Feeding in the 20th Century: Formula and Beikost J. Nutr., February 1, 2001; 131(2): 409S - 420. [Abstract] [Full Text]
|
|
|
|
|
|
L. Davidsson, P. Kastenmayer, H. Szajewska, R. F Hurrell, and D. Barclay Iron bioavailability in infants from an infant cereal fortified with ferric pyrophosphate or ferrous fumarate Am. J. Clinical Nutrition, June 1, 2000; 71(6): 1597 - 1602. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
M. Sattarzadeh and S. H. Zlotkin Iron Is Well Absorbed by Healthy Adults after Ingestion of Double-Fortified (Iron and Dextran-Coated Iodine) Table Salt and Urinary Iodine Excretion Is Unaffected J. Nutr., January 1, 1999; 129(1): 117 - 121. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
L. Davidsson, A. Almgren, and R. F. Hurrell Sodium Iron EDTA [NaFe(III)EDTA] as a Food Fortificant Does Not Influence Absorption and Urinary Excretion of Manganese in Healthy Adults J. Nutr., July 1, 1998; 128(7): 1139 - 1143. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 J. Ortuno, G. Ros, M.J. Periago, C. Martinez, and G. Lopez Biodisponibilidad del selenio y metodos de evaluacion/Selenium bioavailability and methods of evaluation Food Science and Technology International, January 1, 1996; 2(3): 135 - 150. [PDF]
|
|
| HOME | HELP | FEEDBACK | SUBSCRIPTIONS | ARCHIVE | SEARCH | TABLE OF CONTENTS |
