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American Journal of Clinical Nutrition, Vol 5, 26-28, Copyright © 1957 by The American Society for Clinical Nutrition, Inc.

Diabetic Retinopathy: Lack of Correlation with Vitamin B12 Excretion

JOHN J. BOOKMAN M.D.1, ROBERT H. JOELSON M.D.1, WILLIAM G. TOLL M.D.1, HERMAN BAKER PH.D.1, and HENRY DOLGER M.D.1

1 From the Diabetic Service of the Department of Medicine and the Department of Chemistry of The Mount Sinai Hospital, New York, N. Y.

In this study 50 µg of vitamin B12 was injected intramuscularly into three groups of subjects, consisting of normals, diabetic patients without retinopathy, and diabetics with retinopathy. Using three microbiologic methods of analysis, no statistically significant differences were found in the amount excreted in the urine in eight hours among the three groups. The previously reported difference in vitamin B12 excretion by diabetic patients with retinopathy versus those without retinopathy could not be confirmed.







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Copyright © 1957 by The American Society for Nutrition