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American Journal of Clinical Nutrition, Vol 5, 251-259, Copyright © 1957 by The American Society for Clinical Nutrition, Inc.

The Metabolic Availability of Glucose Monoaleuritate

HARRY H. LEVEEN M.D.1

1 From The Department of Surgery, Chicago Medical School

Glucose monoaleuritate is a completely water-soluble ester of aleuritic acid (tri-hydroxy-palmitic acid). The hydroxylated groups on the large carbon chain render it polar, hence the water-soluble ester has no detergent properties. For that reason, it does not cause hemolysis of cells and is non-toxic upon injection into rats. It has a caloric value midway between fat and carbohydrate, but because of its large molecular size, high concentrations of glucose monoaleuritate are not hypertonic. It can be infused without the danger of vascular sclerosis. The parenterally injected material supplies the theoretic number of calories and makes possible growth and development on a diet which would otherwise fail to support life.






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Copyright © 1957 by The American Society for Nutrition