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American Journal of Clinical Nutrition, Vol 5, 453-460, Copyright © 1957 by The American Society for Clinical Nutrition, Inc.
1 Professor and Chairman, Dept. of Anatomy, University of Cincinnati College of Medicine, Cincinnati, Ohio
2 Assistant Professor of Anatomy, Dept. of Anatomy, University of Cincinnati College of Medicine, Cincinnati, Ohio
The hypophysis has a profound influence on erythropoiesis which we believe to be secondary rather than primary. Post-hypophysectomy anemia, in our opinion, develops because of the loss of thyrotropic and adrenocorticotropic hormones and possibly of growth hormone. A theory has been presented that the loss of these hormones finally results in a decreased need for oxygen by the tissues which, in turn, causes a decrease in the rate of erythropoiesis in these animals.
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