American Journal of Clinical Nutrition, Vol 50, 474-478, Copyright © 1989 by The American Society for Clinical Nutrition, Inc

ORIGINAL RESEARCH COMMUNICATIONS

Metabolic effects of adding sucrose and aspartame to the diet of subjects with noninsulin-dependent diabetes mellitus

S Colagiuri, JJ Miller and RA Edwards
Department of Endocrinology and Metabolism, Prince of Wales Hospital, Randwick, NSW, Australia.

This study compared the effects of adding sucrose and aspartame to the usual diet of individuals with well-controlled noninsulin-dependent diabetes mellitus (NIDDM). A double-blind, cross-over design was used with each 6-wk study period. During the sucrose period, 45 g sucrose (9% of total daily energy) was added, 10 g with each main meal and 5 g with each between-meal beverage. An equivalent sweetening quantity of aspartame (162 mg) was ingested during the aspartame period. The addition of sucrose did not have a deleterious effect on glycemic control, lipids, glucose tolerance, or insulin action. No differences were observed between sucrose and aspartame. Sucrose added as an integral part of the diabetic diet does not adversely affect metabolic control in well-controlled NIDDM subjects. Aspartame is an acceptable sugar substitute for diabetic individuals but no specific advantage over sucrose was demonstrated.

This article has been cited by other articles:

				R. J. Manders, B. Pennings, C. P. Beckers, T. I Aipassa, and L. J. van Loon Prevalence of daily hyperglycemia in obese type 2 diabetic men compared with that in lean and obese normoglycemic men: effect of consumption of a sucrose-containing beverage Am. J. Clinical Nutrition, September 1, 2009; 90(3): 511 - 518. [Abstract] [Full Text] [PDF]

				A. Ferland, P. Brassard, and P. Poirier Is Aspartame Really Safer in Reducing the Risk of Hypoglycemia During Exercise in Patients With Type 2 Diabetes? Diabetes Care, July 1, 2007; 30(7): e59 - e59. [Full Text] [PDF]

				R. N. A. Black, M. Spence, R. O. McMahon, G. J. Cuskelly, C. N. Ennis, D. R. McCance, I. S. Young, P. M. Bell, and S. J. Hunter Effect of Eucaloric High- and Low-Sucrose Diets With Identical Macronutrient Profile on Insulin Resistance and Vascular Risk: A Randomized Controlled Trial Diabetes, December 1, 2006; 55(12): 3566 - 3572. [Abstract] [Full Text] [PDF]

				D. E Kelley Sugars and starch in the nutritional management of diabetes mellitus Am. J. Clinical Nutrition, October 1, 2003; 78(4): 858S - 864. [Abstract] [Full Text] [PDF]

				M. J. Franz, J. P. Bantle, C. A. Beebe, J. D. Brunzell, J.-L. Chiasson, A. Garg, L. A. Holzmeister, B. Hoogwerf, E. Mayer-Davis, A. D. Mooradian, et al. Evidence-Based Nutrition Principles and Recommendations for the Treatment and Prevention of Diabetes and Related Complications Diabetes Care, January 1, 2002; 25(1): 148 - 198. [Full Text] [PDF]

				M. J. Franz Nutrition Update: Avoiding Sugar: Does Research Support Traditional Beliefs? The Diabetes Educator, January 1, 1993; 19(2): 144 - 150. [PDF]