AJCN Tufts Nutrition Symposium, Boston Sept 24-26
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

This Article
Right arrow Full Text (PDF)
Right arrow Purchase Article
Right arrow View Shopping Cart
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Shizgal, H. M.
Right arrow Articles by Posner, B.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Shizgal, H. M.
Right arrow Articles by Posner, B.
Agricola
Right arrow Articles by Shizgal, H. M.
Right arrow Articles by Posner, B.

American Journal of Clinical Nutrition, Vol 50, 1355-1363, Copyright © 1989 by The American Society for Clinical Nutrition, Inc

ORIGINAL RESEARCH COMMUNICATIONS

Insulin and the efficacy of total parenteral nutrition

HM Shizgal and B Posner
Department of Surgery, Royal Victoria Hospital, Montreal, Quebec, Canada.

This study examined the effect of insulin on the efficacy of total parenteral nutrition (TPN). Patients were randomized to receive either crystalline zinc insulin (CZI) in each liter of TPN solution (insulin group) or no additional insulin (control group). The efficacy of TPN was evaluated by measuring body composition at 2-wk intervals. In malnourished patients the body cell mass (BCM) increased significantly with 2 wk of TPN both with and without additional insulin. The rate of change of BCM was correlated to the total caloric intake, serum insulin concentration, age, and nutritional state. The resulting multiple linear regression demonstrated that the restoration of a depleted BCM was directly related to the caloric intake, plasma insulin concentration, and degree of malnutrition and was inversely related to age. The addition of insulin to TPN solutions increases the rate at which a malnourished state is corrected.




HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Copyright © 1989 by The American Society for Nutrition