| HOME | HELP | FEEDBACK | SUBSCRIPTIONS | ARCHIVE | SEARCH | TABLE OF CONTENTS |
|
|
|
|||||||
|
|||||||||
American Journal of Clinical Nutrition, Vol 53, 899-907, Copyright © 1991 by The American Society for Clinical Nutrition, Inc
ORIGINAL RESEARCH COMMUNICATIONS |
EM Berry, S Eisenberg, D Haratz, Y Friedlander, Y Norman, NA Kaufmann and Y Stein
Department of Medicine B, Hadassah University Hospital, Jerusalem, Israel.
Twenty-six Yeshiva students were randomly assigned to a 24-wk crossover study of monounsaturated fatty acid (MUFA) vs polyunsaturated fatty acid (PUFA) diets (50% carbohydrate, 32% fat, 18% protein) fed alternately during two 12-wk periods. Total plasma cholesterol (TC) decreased significantly by approximately 10% and approximately 16% on the MUFA and PUFA diets, respectively. Plasma triglyceride response was variable. Low-density-lipoprotein cholesterol (LDL-C) decreased in both groups with an additional significant effect between periods. Concentrations of high-density-lipoprotein cholesterol did not change significantly. LDL-receptor status in fresh monocytes, affinity of LDL towards the LDL receptor in cultured fibroblasts, zonal-centrifugation profiles, and lipoprotein composition were not significantly different between the diets. There was a significantly higher tendency toward lipid peroxidation on the PUFA diet, as ascertained by more thiobarbituric acid-reactive-substances formation on that diet. Dietary PUFA results in somewhat lower TC and LDL-C concentrations whereas with MUFA the susceptibility of LDL to oxidative stress is lower.
This article has been cited by other articles:
|
|
 |
|
  M. J. Sheridan, J. N. Cooper, M. Erario, and C. E. Cheifetz Pistachio Nut Consumption and Serum Lipid Levels J. Am. Coll. Nutr., April 1, 2007; 26(2): 141 - 148. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 T. Tholstrup, L. I. Hellgren, M. Petersen, S. Basu, E. M. Straarup, P. Schnohr, and B. Sandstrom A Solid Dietary Fat Containing Fish Oil Redistributes Lipoprotein Subclasses without Increasing Oxidative Stress in Men J. Nutr., May 1, 2004; 134(5): 1051 - 1057. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
M. Sagara, T. Kanda, M. NJelekera, T. Teramoto, L. Armitage, N. Birt, C. Birt, and Y. Yamori Effects of Dietary Intake of Soy Protein and Isoflavones on Cardiovascular Disease Risk Factors in High Risk, Middle-Aged Men in Scotland J. Am. Coll. Nutr., February 1, 2004; 23(1): 85 - 91. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 R. P Mensink, P. L Zock, A. D. Kester, and M. B Katan Effects of dietary fatty acids and carbohydrates on the ratio of serum total to HDL cholesterol and on serum lipids and apolipoproteins: a meta-analysis of 60 controlled trials Am. J. Clinical Nutrition, May 1, 2003; 77(5): 1146 - 1155. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
C. M. Alper and R. D. Mattes Peanut Consumption Improves Indices of Cardiovascular Disease Risk in Healthy Adults J. Am. Coll. Nutr., April 1, 2003; 22(2): 133 - 141. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
M. L. Garg, R. J. Blake, and R. B. H. Wills Macadamia Nut Consumption Lowers Plasma Total and LDL Cholesterol Levels in Hypercholesterolemic Men J. Nutr., April 1, 2003; 133(4): 1060 - 1063. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
J. L Derstine, L. E Murray-Kolb, S. Yu-Poth, R. L Hargrove, P. M Kris-Etherton, and J. L Beard Iron status in association with cardiovascular disease risk in 3 controlled feeding studies Am. J. Clinical Nutrition, January 1, 2003; 77(1): 56 - 62. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
L. G Wood, D. A Fitzgerald, A. K Lee, and M. L Garg Improved antioxidant and fatty acid status of patients with cystic fibrosis after antioxidant supplementation is linked to improved lung function Am. J. Clinical Nutrition, January 1, 2003; 77(1): 150 - 159. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
R. Freese, G. Alfthan, M. Jauhiainen, S. Basu, I. Erlund, I. Salminen, A. Aro, and M. Mutanen High intakes of vegetables, berries, and apples combined with a high intake of linoleic or oleic acid only slightly affect markers of lipid peroxidation and lipoprotein metabolism in healthy subjects Am. J. Clinical Nutrition, November 1, 2002; 76(5): 950 - 960. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
E. B. Feldman The Scientific Evidence for a Beneficial Health Relationship Between Walnuts and Coronary Heart Disease J. Nutr., May 1, 2002; 132(5): 1062S - 1101. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
L. G Wood, D. A Fitzgerald, P. G Gibson, D. M Cooper, and M. L Garg Increased plasma fatty acid concentrations after respiratory exacerbations are associated with elevated oxidative stress in cystic fibrosis patients Am. J. Clinical Nutrition, April 1, 2002; 75(4): 668 - 675. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 D. R. Smith, R. Wood, S. Tseng, and S. B. Smith Increased Beef Consumption Increases Apolipoprotein A-I but Not Serum Cholesterol of Mildly Hypercholesterolemic Men with Different Levels of Habitual Beef Intake Experimental Biology and Medicine, April 1, 2002; 227(4): 266 - 275. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
T. Gulesserian and K. Widhalm Effect of a Rapeseed Oil Substituting Diet on Serum Lipids and Lipoproteins in Children and Adolescents with Familial Hypercholesterolemia J. Am. Coll. Nutr., April 1, 2002; 21(2): 103 - 108. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
J. W Stewart, M. L Kaplan, and D. C Beitz Pork with a high content of polyunsaturated fatty acids lowers LDL cholesterol in women Am. J. Clinical Nutrition, August 1, 2001; 74(2): 179 - 187. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
R. U Almario, V. Vonghavaravat, R. Wong, and S. E Kasim-Karakas Effects of walnut consumption on plasma fatty acids and lipoproteins in combined hyperlipidemia Am. J. Clinical Nutrition, July 1, 2001; 74(1): 72 - 79. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 E.M. Berry Are diets high in omega-6 polyunsaturated fatty acids unhealthy? Eur. Heart J. Suppl., June 1, 2001; 3(suppl_D): D37 - D41. [Abstract] [PDF]
|
|
|
|
 |
|
 J. V. Higdon, S. H. Du, Y. S. Lee, T. Wu, and R. C. Wander Supplementation of postmenopausal women with fish oil does not increase overall oxidation of LDL ex vivo compared to dietary oils rich in oleate and linoleate J. Lipid Res., March 1, 2001; 42(3): 407 - 418. [Abstract] [Full Text]
|
|
|
|
|
|
E. Amusquivar, F. J. Ruperez, C. Barbas, and E. Herrera Low Arachidonic Acid Rather than {alpha}-Tocopherol Is Responsible for the Delayed Postnatal Development in Offspring of Rats Fed Fish Oil Instead of Olive Oil during Pregnancy and Lactation J. Nutr., November 1, 2000; 130(11): 2855 - 2865. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
S. Yu-Poth, T. D. Etherton, C. C. Reddy, T. A. Pearson, R. Reed, G. Zhao, S. Jonnalagadda, Y. Wan, and P. M. Kris-Etherton Lowering Dietary Saturated Fat and Total Fat Reduces the Oxidative Susceptibility of LDL in Healthy Men and Women J. Nutr., September 1, 2000; 130(9): 2228 - 2237. [Abstract] [Full Text]
|
|
|
|
|
|
S.-C. Lu, W.-H. Wu, C.-A. Lee, H.-F. Chou, H.-R. Lee, and P.-C. Huang LDL of Taiwanese Vegetarians Are Less Oxidizable than Those of Omnivores J. Nutr., June 1, 2000; 130(6): 1591 - 1596. [Abstract] [Full Text]
|
|
|
|
 |
|
 J. D. Curb, G. Wergowske, J. C. Dobbs, R. D. Abbott, and B. Huang Serum Lipid Effects of a High-Monounsaturated Fat Diet Based on Macadamia Nuts Arch Intern Med, April 24, 2000; 160(8): 1154 - 1158. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
J. Eritsland Safety considerations of polyunsaturated fatty acids Am. J. Clinical Nutrition, January 1, 2000; 71(1): 197S - 201S. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
O. Goulet, S. de Potter, H. Antebi, F. Driss, V. Colomb, G. Bereziat, L.-G. Alcindor, O. Corriol, A. Le Brun, G. Dutot, et al. Long-term efficacy and safety of a new olive oil–based intravenous fat emulsion in pediatric patients: a double-blind randomized study Am. J. Clinical Nutrition, September 1, 1999; 70(3): 338 - 345. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
P. M Kris-Etherton, S. Yu-Poth, J. Sabate, H. E Ratcliffe, G. Zhao, and T. D Etherton Nuts and their bioactive constituents: effects on serum lipids and other factors that affect disease risk Am. J. Clinical Nutrition, September 1, 1999; 70(3): 504S - 511. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
K. P. Navder, E. Baraona, M. A. Leo, and C. S. Lieber Oxidation of LDL in baboons is increased by alcohol and attenuated by polyenylphosphatidylcholine J. Lipid Res., June 1, 1999; 40(6): 983 - 987. [Abstract] [Full Text]
|
|
|
|
 |
|
 S. Tsimikas, A. Philis-Tsimikas, S. Alexopoulos, F. Sigari, C. Lee, and P. D. Reaven LDL Isolated From Greek Subjects on a Typical Diet or From American Subjects on an Oleate-Supplemented Diet Induces Less Monocyte Chemotaxis and Adhesion When Exposed to Oxidative Stress Arterioscler. Thromb. Vasc. Biol., January 1, 1999; 19(1): 122 - 130. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
L. Frémont, M. T. Gozzélino, M. P. Franchi, and A. Linard Dietary Flavonoids Reduce Lipid Peroxidation in Rats Fed Polyunsaturated or Monounsaturated Fat Diets J. Nutr., September 1, 1998; 128(9): 1495 - 1502. [Abstract] [Full Text]
|
|
|
|
|
|
C. Lee, J. Barnett, and P. D. Reaven Liposomes enriched in oleic acid are less susceptible to oxidation and have less proinflammatory activity when exposed to oxidizing conditions J. Lipid Res., June 1, 1998; 39(6): 1239 - 1247. [Abstract] [Full Text]
|
|
|
|
|
|
G. A. Spiller, D. A. J. Jenkins, O. Bosello, J. E. Gates, L. N. Cragen, and B. Bruce Nuts and Plasma Lipids: An Almond-Based Diet Lowers LDL-C while Preserving HDL-C J. Am. Coll. Nutr., June 1, 1998; 17(3): 285 - 290. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
L. P. L. van de Vijver, A. F. M. Kardinaal, W. van Duyvenvoorde, D. A. C. M. Kruijssen, D. E. Grobbee, G. van Poppel, and H. M. G. Princen LDL Oxidation and Extent of Coronary Atherosclerosis Arterioscler. Thromb. Vasc. Biol., February 1, 1998; 18(2): 193 - 199. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
I. R. Brude, C. A. Drevon, I. Hjermann, I. Seljeflot, S. Lund-Katz, K. Saarem, B. Sandstad, K. Solvoll, B. Halvorsen, H. Arnesen, et al. Peroxidation of LDL From Combined-Hyperlipidemic Male Smokers Supplied With ¯-3 Fatty Acids and Antioxidants Arterioscler. Thromb. Vasc. Biol., November 1, 1997; 17(11): 2576 - 2588. [Abstract] [Full Text]
|
|
|
|
|
|
M.-F. Hau, A. H.M. Smelt, A. J.G.H. Bindels, E. J.G. Sijbrands, A. Van der Laarse, W. Onkenhout, W. van Duyvenvoorde, and H. M.G. Princen Effects of Fish Oil on Oxidation Resistance of VLDL in Hypertriglyceridemic Patients Arterioscler. Thromb. Vasc. Biol., September 1, 1996; 16(9): 1197 - 1202. [Abstract] [Full Text]
|
|
|
|
|
|
C. D. Gardner and H. C. Kraemer Monounsaturated Versus Polyunsaturated Dietary Fat and Serum Lipids : A Meta-analysis Arterioscler. Thromb. Vasc. Biol., November 1, 1995; 15(11): 1917 - 1927. [Abstract] [Full Text]
|
|
|
|
 |
|
 S. C. Rumsey, N. F. Galeano, B. Lipschitz, and R. J. Deckelbaum Oleate and Other Long Chain Fatty Acids Stimulate Low Density Lipoprotein Receptor Activity by Enhancing Acyl Coenzyme A:Cholesterol Acyltransferase Activity and Altering Intracellular Regulatory Cholesterol Pools in Cultured Cells J. Biol. Chem., April 28, 1995; 270(17): 10008 - 10016. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
H. M.G. Princen, W. van Duyvenvoorde, R. Buytenhek, A. van der Laarse, G. van Poppel, J. A. G. Leuven, and V. W.M. van Hinsbergh Supplementation With Low Doses of Vitamin E Protects LDL From Lipid Peroxidation in Men and Women Arterioscler. Thromb. Vasc. Biol., March 1, 1995; 15(3): 325 - 333. [Abstract] [Full Text]
|
|
|
|
 |
|
 A A Rivellese, P Auletta, G Marotta, G Saldalamacchia, A Giacoo, V Mastrilli, O Vaccaro, and G Riccardi Long term metabolic effects of two dietary methods of treating hyperlipidaemia BMJ, January 22, 1994; 308(6923): 227 - 231. [Abstract] [Full Text]
|
|
|
|
|
|
R. S. Rosenson Low Levels of High-Density Lipoprotein Cholesterol (Hypoalphalipoproteinemia) An Approach to Management Arch Intern Med, July 12, 1993; 153(13): 1528 - 1538. [Abstract] [PDF]
|
|
| HOME | HELP | FEEDBACK | SUBSCRIPTIONS | ARCHIVE | SEARCH | TABLE OF CONTENTS |
