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American Journal of Clinical Nutrition, Vol 54, 359-362, Copyright © 1991 by The American Society for Clinical Nutrition, Inc
ORIGINAL RESEARCH COMMUNICATIONS |
BJ Burri, RM Dougherty, DS Kelley and JM Iacono
US Department of Agriculture/Agriculture Research Service, Western Human Nutrition Research Center, Presidio of San Francisco, CA 94129.
The effect of concentrations of linoleic acid (LA) on platelet aggregation was measured in seven healthy adult males. Subjects were randomly divided into two groups; these groups were fed natural food diets of identical composition except that one was high in LA (11.5% of energy) and low in oleic acid (OA) (7.4% of energy), the other was low in LA (4.5% of energy) and high in OA (15.7% of energy). The thresholds of ADP- and collagen-induced platelet aggregation were increased significantly by the high LA diet even though the intake of total fat and saturated fatty acids did not differ in these diets.
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