American Journal of Clinical Nutrition, Vol 55, 689-694, Copyright © 1992 by The American Society for Clinical Nutrition, Inc

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Plasma lipid and lipoprotein concentrations of men consuming a low-fat, high-fiber diet

BA Clevidence, JT Judd, A Schatzkin, RA Muesing, WS Campbell, CC Brown and PR Taylor
Lipid Nutrition Laboratory, Beltsville Human Nutrition Research Center, ARS, USDA, MD 20705.

This study assessed the influence of a low-fat, high-fiber diet on blood lipid concentrations of 42 men with desirable or moderately elevated cholesterol concentrations. A low-fat diet (19% fat, 4% saturated fatty acids, 4.6 g fiber/MJ) was compared with a high-fat diet (41% fat, 15% saturated fatty acids, 2.0 g fiber/MJ) and with subjects' self-selected diets. Substituting the low-fat for the high- fat diet decreased total, low-density-lipoprotein, and high-density- lipoprotein cholesterol by 17-20%. Lipid changes between 6 and 10 wk were minor. A reduction in plasma cholesterol of greater than 0.52 mmol/L was achieved with the low-fat diet in 59% of men changing from their self-selected diets and in 79% changing from the high-fat diet. Percent reduction was independent of subjects' cholesterol classification. Results indicate that significant reductions in plasma cholesterol can be achieved by the majority of men committing to a low- fat, high-fiber diet.

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