American Journal of Clinical Nutrition, Vol 55, 896-901, Copyright © 1992 by The American Society for Clinical Nutrition, Inc

ORIGINAL RESEARCH COMMUNICATIONS

Effects on plasma lipoproteins and endogenous sex hormones of substituting lean white fish for other animal-protein sources in diets of postmenopausal women

H Jacques, L Noreau and S Moorjani
Departement de nutrition humaine et de consommation, Universite Laval, Quebec, Canada.

A crossover 8-wk study was conducted to compare the effects on plasma lipoproteins and endogenous sex hormones of lean white fish (LWF) and of beef, pork, egg, and milk (BPEM) within a prudent diet in postmenopausal women. Diets provided 8050 kJ as 19% proteins, 52% carbohydrates, 29% lipids (P/M/S (proportion of polyunsaturated, monounsaturated, and saturated fatty acids, 1.1:1:1) and approximately 210 mg cholesterol/d. The LWF diet compared with the BPEM diet significantly induced higher concentrations of plasma cholesterol, LDL- apo B, HDL-C, and HDL3-C, indicating that incorporation of LWF as a substitute for BPEM in a low-fat, high-P:S diet offers little benefit with regard to plasma cholesterol and LDL-apoB in postmenopausal women. Moreover, the LWF diet significantly increased plasma SHBG, suggesting that the divergent effects of substituting LWF for other animal-protein sources on plasma cholesterol and lipoproteins may be partly mediated by variations in plasma sex-hormone status.

This article has been cited by other articles:

				W. S Harris, J. V Pottala, S. A Sands, and P. G Jones Comparison of the effects of fish and fish-oil capsules on the n 3 fatty acid content of blood cells and plasma phospholipids Am. J. Clinical Nutrition, December 1, 2007; 86(6): 1621 - 1625. [Abstract] [Full Text] [PDF]

				I. Demonty, Y. Deshaies, B. Lamarche, and H. Jacques Cod Protein Lowers the Hepatic Triglyceride Secretion Rate in Rats J. Nutr., May 1, 2003; 133(5): 1398 - 1402. [Abstract] [Full Text] [PDF]

				E. Beauchesne-Rondeau, A. Gascon, J. Bergeron, and H. Jacques Plasma lipids and lipoproteins in hypercholesterolemic men fed a lipid-lowering diet containing lean beef, lean fish, or poultry Am. J. Clinical Nutrition, March 1, 2003; 77(3): 587 - 593. [Abstract] [Full Text] [PDF]

				C. Lavigne, F. Tremblay, G. Asselin, H. Jacques, and A. Marette Prevention of skeletal muscle insulin resistance by dietary cod protein in high fat-fed rats Am J Physiol Endocrinol Metab, July 1, 2001; 281(1): E62 - E71. [Abstract] [Full Text] [PDF]

				W.S. Harris Omega-3 long-chain PUFA and triglyceride lowering: minimum effective intakes Eur. Heart J. Suppl., June 1, 2001; 3(suppl_D): D59 - D61. [Abstract] [PDF]

				B. Lacaille, P. Julien, Y. Deshaies, C. Lavigne, L.-D Brun, and H. Jacques Responses of Plasma Lipoproteins and Sex Hormones to the Consumption of Lean Fish Incorporated in a Prudent-Type Diet in Normolipidemic Men J. Am. Coll. Nutr., June 1, 2000; 19(6): 745 - 753. [Abstract] [Full Text] [PDF]