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American Journal of Clinical Nutrition, Vol 55, 1244S-1245S, Copyright © 1992 by The American Society for Clinical Nutrition, Inc

REVIEW ARTICLES

Nutrition and genetic susceptibility to common diseases

AG Motulsky
Department of Medicine and Genetics, University of Washington, Seattle 98195.

Genetic factors play a role in chronic disease and conditions such as coronary heart disease, hypertension, and obesity. Individual responses to nutritional factors involved in such conditions vary depending upon a person's genetic make-up. The role of individual genes is best understood for the hyperlipidemias that predispose to coronary heart disease. Until more and better information on gene-nutritional interactions is available, general population-wide recommendations regarding a prudent diet appear reasonable. At the same time, high risk screening for certain conditions such as the hyperlipidemias is appropriate.




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Copyright © 1992 by The American Society for Nutrition