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American Journal of Clinical Nutrition, Vol 56, 244S-246S, Copyright © 1992 by The American Society for Clinical Nutrition, Inc
ORIGINAL RESEARCH COMMUNICATIONS |
JW Anderson, VL Brinkman and CC Hamilton
Endocrine-Metabolic Section, VA Medical Center, Lexington, KY 40511.
Eighty morbidly obese individuals consecutively enrolled in a comprehensive very-low-calorie diet (VLCD) program were evaluated. Patients' mean initial body mass index was 45.5 kg/m2 and they lost 35.3 kg in 26 wk. Serum total cholesterol, low-density-lipoprotein cholesterol, and triglycerides decreased by 15.0%, 17.0%, and 14%, respectively. Systolic and diastolic blood pressure decreased by 8.7% and 10.0%, respectively. The 46 individuals completing 2-y follow-up were maintaining 48.0 +/- 7.6% (means +/- SE) of their weight loss. Morbidly obese persons lost substantial amounts of weight using a comprehensive VLCD program, reduced risk factors associated with obesity, and had encouraging long-term results, with 48% of weight loss maintained at 2 y of follow-up.
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