AJCN North Carolina Research Campus
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

This Article
Right arrow Full Text (PDF)
Right arrow Purchase Article
Right arrow View Shopping Cart
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by McCall, M. R.
Right arrow Articles by Foster, D. M.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by McCall, M. R.
Right arrow Articles by Foster, D. M.
Agricola
Right arrow Articles by McCall, M. R.
Right arrow Articles by Foster, D. M.

American Journal of Clinical Nutrition, Vol 56, 376-384, Copyright © 1992 by The American Society for Clinical Nutrition, Inc

ORIGINAL RESEARCH COMMUNICATIONS

Psyllium husk. I: Effect on plasma lipoproteins, cholesterol metabolism, and atherosclerosis in African green monkeys

MR McCall, T Mehta, CW Leathers and DM Foster
Department of Food Science, Washington State University, Pullman.

Psyllium's effects on plasma and lipoprotein cholesterol concentrations, cholesterol metabolism, and diet-induced atherosclerosis were studied in adult male African green monkeys (Cercopithecus aethiops). Animals were fed for 3.5 y one of three experimental diets: low-cholesterol cellulose (LCC), high-cholesterol cellulose (HCC), or high-cholesterol psyllium (HCP). The LCC and HCP groups had significantly (P less than 0.05) lower plasma cholesterol concentrations (39% lower) at 1 mo than did the HCC group. These responses persisted throughout the study. Plasma cholesterol changes were due to a reduction in intermediate-density and low-density lipoproteins; very-low and high-density-lipoprotein concentrations were similar among groups. Aortic atherosclerosis, evaluated as percent sudanophilia at 3.5 y, was lowest in the LCC group, intermediate in the HCP group, and highest in the HCC group. Cholesterol absorption, neutral steroid and fat excretion, HMGCoA reductase activity (in intestine and liver), and body weight were unrelated to psyllium's hypocholesterolemic effects.


This article has been cited by other articles:


Home page
 J. Nutr.Home page
S. Vega-Lopez, H. C. Freake, and M. L. Fernandez
Sex and Hormonal Status Modulate the Effects of Psyllium on Plasma Lipids and Monocyte Gene Expression in Humans
J. Nutr., January 1, 2003; 133(1): 67 - 70.
[Abstract] [Full Text] [PDF]

Home page
 J. Nutr.Home page
E. A. Trautwein, A. Kunath-Rau, and H. F. Erbersdobler
Increased Fecal Bile Acid Excretion and Changes in the Circulating Bile Acid Pool Are Involved in the Hypocholesterolemic and Gallstone-Preventive Actions of Psyllium in Hamsters
J. Nutr., April 1, 1999; 129(4): 896 - 902.
[Abstract] [Full Text]

Home page
 J. Nutr.Home page
A.H.M. Terpstra, J. A. Lapre, H. T. de Vries, and A. C. Beynen
Dietary Pectin with High Viscosity Lowers Plasma and Liver Cholesterol Concentration and Plasma Cholesteryl Ester Transfer Protein Activity in Hamsters
J. Nutr., November 1, 1998; 128(11): 1944 - 1949.
[Abstract] [Full Text]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Copyright © 1992 by The American Society for Nutrition