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American Journal of Clinical Nutrition, Vol 57, 640-642, Copyright © 1993 by The American Society for Clinical Nutrition, Inc

ORIGINAL RESEARCH COMMUNICATIONS

Marked increase in plasma high-density-lipoprotein cholesterol after prolonged fasting during Ramadan

M Maislos, N Khamaysi, A Assali, Y Abou-Rabiah, I Zvili and S Shany
Department of Medicine, Tour Institute, Soroka Medical Center, Ben- Gurion University Faculty of Health Sciences, Beer Sheva, Israel.

We evaluated the effect of the Ramadan fasting on plasma lipids and lipoproteins in normal individuals. Twenty-four healthy subjects were studied before the end of the Ramadan month (Ram) and for 1 mo thereafter. Plasma total cholesterol (TC), triglycerides, low-density- lipoprotein cholesterol (LDL-C), and very-low-density-lipoprotein cholesterol (VLDL-C) did not change. High-density-lipoprotein cholesterol (HDL-C) was 30% higher (P < 0.005) at the end of Ram; apolipoprotein A-I also increased (P < 0.0001). Both the ratios of TC to HDL-C and LDL-C to HDL-C (P < 0.001) decreased at Ram. There was a striking nonpharmacologic improvement in plasma HDL-C and ratios of TC to HDL-C and LDL-C to HDL-C, which were most probably induced by eating one large evening meal a day. Further studies to determine the mechanism of this observation are underway.


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N. Najib, D. Laraque, and J. Leung
Failure to Thrive During Ramadan: A Patient Report
Clinical Pediatrics, June 1, 1996; 35(6): 323 - 325.
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