American Journal of Clinical Nutrition, Vol 59, 389-394, Copyright © 1994 by The American Society for Clinical Nutrition, Inc

ORIGINAL RESEARCH COMMUNICATIONS

Effect of rye bran on excretion of bile acids, cholesterol, nitrogen, and fat in human subjects with ileostomies

JX Zhang, E Lundin, G Hallmans, H Adlercreutz, H Andersson, I Bosaeus, P Aman, R Stenling and S Dahlgren
Department of Pathology, University of Umea, Sweden.

The excretion of bile acids, cholesterol, dry matter, nitrogen, fat, and energy in ileostomy effluent, and plasma lipid concentrations were studied in eight subjects with ileostomies. The subjects consumed a wheat bread-based, low-fiber diet (LFD) for 3 wk and a rye bran bread- based, high-fiber diet (HFD) for 3 wk. The ileal excretion of dry matter, nitrogen, fat, and energy was higher during the HFD period. The daily excretion and the percentage of conjugated bile acids were significantly higher and the percentage of free bile acids lower in the ileostomy effluents during the HFD as compared with the LFD period. No significant difference in the excretion of cholesterol, net cholesterol, sterol, or net sterol was noted between the HFD and LFD periods. No significant differences in plasma concentrations of HDL-, LDL-, and total cholesterol, and apolipoprotein A-I and B were observed between the two 3-wk dietary periods.

This article has been cited by other articles:

				S. M. Gråsten, K. S. Juntunen, K. S. Poutanen, H. K. Gylling, T. A. Miettinen, and H. M. Mykkänen Rye Bread Improves Bowel Function and Decreases the Concentrations of Some Compounds That Are Putative Colon Cancer Risk Markers in Middle-Aged Women and Men J. Nutr., September 1, 2000; 130(9): 2215 - 2221. [Abstract] [Full Text]

				K. S. Leinonen, K. S. Poutanen, and H. M. Mykkänen Rye Bread Decreases Serum Total and LDL Cholesterol in Men with Moderately Elevated Serum Cholesterol J. Nutr., January 1, 2000; 130(2): 164 - 170. [Abstract] [Full Text]