AJCN Cancer Health Disparities Conference
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

This Article
Right arrow Full Text (PDF)
Right arrow Purchase Article
Right arrow View Shopping Cart
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Right arrow Citation Map
Services
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Marckmann, P.
Right arrow Articles by Jespersen, J.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Marckmann, P.
Right arrow Articles by Jespersen, J.
Agricola
Right arrow Articles by Marckmann, P.
Right arrow Articles by Jespersen, J.

American Journal of Clinical Nutrition, Vol 59, 935-939, Copyright © 1994 by The American Society for Clinical Nutrition, Inc

ORIGINAL RESEARCH COMMUNICATIONS

Low-fat, high-fiber diet favorably affects several independent risk markers of ischemic heart disease: observations on blood lipids, coagulation, and fibrinolysis from a trial of middle-aged Danes

P Marckmann, B Sandstrom and J Jespersen
Research Department of Human Nutrition, Royal Veterinary and Agricultural University, Frederiksberg, Denmark.

We served a low-fat (28% of energy), high-fiber (3.3 g/MJ) diet according to Nordic nutrition recommendations (Rec diet), and a high- fat diet (39% of energy) corresponding to the average Danish diet (Dane diet) for periods of 2 wk in a randomized crossover study of 21 healthy middle-aged individuals. The Rec diet resulted in lower serum concentrations of low-density-lipoprotein (LDL) cholesterol (medians: 2.77 vs 3.04 mmol/L, P < 0.001) and high-density-lipoprotein (HDL) cholesterol (1.08 vs 1.24 mmol/L, P < 0.001), and higher fasting triglycerides (1.11 vs 0.86 mmol/L, P = 0.04) than did the Dane diet. Furthermore, the Rec diet lowered plasma factor VII coagulant activity (FVIIc) (88% vs 96%, P = 0.002) and raised plasma fibrinolytic activity. Our observations indicate that a low-fat, high-fiber diet may not only reduce the atherogenic but also the thrombogenic tendency of an individual compared with a diet corresponding to the average Danish diet.


This article has been cited by other articles:


Home page
 J. Nutr.Home page
S. A. Atkinson, L. Davidsson, M. Hambidge, B. Lonnerdal, K. F. Michaelsen, and N. Solomons
Brittmarie Sandstrom (1945-2002)
J. Nutr., December 1, 2003; 133(12): 4071 - 4073.
[Full Text] [PDF]

Home page
 J. Nutr.Home page
H. Muller, A. S. Lindman, A. Blomfeldt, I. Seljeflot, and J. I. Pedersen
A Diet Rich in Coconut Oil Reduces Diurnal Postprandial Variations in Circulating Tissue Plasminogen Activator Antigen and Fasting Lipoprotein (a) Compared with a Diet Rich in Unsaturated Fat in Women
J. Nutr., November 1, 2003; 133(11): 3422 - 3427.
[Abstract] [Full Text] [PDF]

Home page
 Am. J. Clin. Nutr.Home page
S. Rajaram
The effect of vegetarian diet, plant foods, and phytochemicals on hemostasis and thrombosis
Am. J. Clinical Nutrition, September 1, 2003; 78(3): 552S - 558.
[Abstract] [Full Text] [PDF]

Home page
 J. Lipid Res.Home page
A. H. Lichtenstein, L. M. Ausman, S. M. Jalbert, M. Vilella-Bach, M. Jauhiainen, S. McGladdery, A. T. Erkkila, C. Ehnholm, J. Frohlich, and E. J. Schaefer
Efficacy of a Therapeutic Lifestyle Change/Step 2 diet in moderately hypercholesterolemic middle-aged and elderly female and male subjects
J. Lipid Res., February 1, 2002; 43(2): 264 - 273.
[Abstract] [Full Text] [PDF]

Home page
 Am. J. Clin. Nutr.Home page
B. Mittendorfer and L. S Sidossis
Mechanism for the increase in plasma triacylglycerol concentrations after consumption of short-term, high-carbohydrate diets
Am. J. Clinical Nutrition, May 1, 2001; 73(5): 892 - 899.
[Abstract] [Full Text] [PDF]

Home page
 Arterioscler. Thromb. Vasc. Bio.Home page
E. M. Bladbjerg, A.-M. Munster, P. Marckmann, N. Keller, and J. Jespersen
Dietary Factor VII Activation Does Not Increase Plasma Concentrations of Prothrombin Fragment 1+2 in Patients With Stable Angina Pectoris and Coronary Atherosclerosis
Arterioscler. Thromb. Vasc. Biol., November 1, 2000; 20(11): 2494 - 2499.
[Abstract] [Full Text] [PDF]

Home page
 J. Nutr.Home page
J. W. Anderson and T. J. Hanna
Impact of Nondigestible Carbohydrates on Serum Lipoproteins and Risk for Cardiovascular Disease
J. Nutr., July 1, 1999; 129(7): 1457 - 1457.
[Abstract] [Full Text]

Home page
 J. Nutr.Home page
L. I. Mennen, M. P. M. de Maat, E. G. Schouten, C. Kluft, J. C. M. Witteman, A. Hofman, and D. E. Grobbee
Dietary Effects on Coagulation Factor VII Vary across Genotypes of the R/Q353 Polymorphism in Elderly People
J. Nutr., May 1, 1998; 128(5): 870 - 874.
[Abstract] [Full Text]

Home page
 Arterioscler. Thromb. Vasc. Bio.Home page
P. Marckmann, E.-M. Bladbjerg, and J. Jespersen
Dietary Fish Oil (4 g Daily) and Cardiovascular Risk Markers in Healthy Men
Arterioscler. Thromb. Vasc. Biol., December 1, 1997; 17(12): 3384 - 3391.
[Abstract] [Full Text]

Home page
 Arterioscler. Thromb. Vasc. Bio.Home page
T. A. B. Sanders, F. R. Oakley, G. J. Miller, K. A. Mitropoulos, D. Crook, and M. F. Oliver
Influence of n-6 versus n-3 Polyunsaturated Fatty Acids in Diets Low in Saturated Fatty Acids on Plasma Lipoproteins and Hemostatic Factors
Arterioscler. Thromb. Vasc. Biol., December 1, 1997; 17(12): 3449 - 3460.
[Abstract] [Full Text]

Home page
 Arterioscler. Thromb. Vasc. Bio.Home page
K. Almendingen, I. Seljeflot, B. Sandstad, and J. I. Pedersen
Effects of Partially Hydrogenated Fish Oil, Partially Hydrogenated Soybean Oil, and Butter on Hemostatic Variables in Men
Arterioscler. Thromb. Vasc. Biol., March 1, 1996; 16(3): 375 - 380.
[Abstract] [Full Text]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Copyright © 1994 by The American Society for Nutrition