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American Journal of Clinical Nutrition, Vol 6, 531-534, Copyright © 1958 by The American Society for Clinical Nutrition, Inc.

Lean-Body Mass Creatinine-Coefficient Deficit and Urinary Steroids

HARRY SOBEL PH.D.1

1 Institute for Medical Research, Cedars of Lebanon Hospital, and the Department of Biochemistry and Nutrition, University of Southern California, Los Angeles

The Lean Body Mass Creatinine Coefficient (–DgrC.C.) is proposed as a device for evaluating nitrogen deficits in individuals who are free of renal, hepatic, and muscular disease and whose correct height is determinable. In a group of men with a variety of chronic illness, large –DgrC.C. values were observed in 29 per cent of the cases in contrast to a similar group of normal men in whom large deficits occurred in only 17 per cent. A relevant finding was the presence of an increased antianabolic influence as determined by urinary steroid studies in patients with large –DgrC.C. values.






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Copyright © 1958 by The American Society for Nutrition