American Journal of Clinical Nutrition, Vol 60, 470-475, Copyright © 1994 by The American Society for Clinical Nutrition, Inc

ORIGINAL RESEARCH COMMUNICATIONS

Effects of isoenergetic, low-fat diets on energy metabolism in lean and obese women

LR Roust, KD Hammel and MD Jensen
Endocrine Research Unit, Mayo Clinic and Foundation, Rochester, MN 55905.

Whether changing from a high-fat diet to an isoenergetic, low-fat, high- complex-carbohydrate diet results in thermogenic benefits is controversial. Brief dietary interventions and failure to account for the potential influence of body-fat distribution on energy metabolism could have confounded the interpretation of previous studies. To address these issues, eight upper-body obese, seven lower-body obese, and eight non-obese premenopausal women underwent measurements of body composition, resting energy expenditure, overnight energy expenditure, and meal fat oxidation at the end of a weight-stabilizing, high-fat (42%) diet, and after 4 wk of an isoenergetic, low-fat (27%) diet. No change in body composition, resting energy expenditure, overnight energy expenditure, or meal fat oxidation occurred. We conclude that isoenergetic shifts from dietary fat to dietary carbohydrate within the generally recommended range have little or no effect on energy metabolism, and that body-fat distribution does not predict differences in energy expenditure.

This article has been cited by other articles:

				C L. Kien, J. Y Bunn, and F. Ugrasbul Increasing dietary palmitic acid decreases fat oxidation and daily energy expenditure Am. J. Clinical Nutrition, August 1, 2005; 82(2): 320 - 326. [Abstract] [Full Text] [PDF]

				M Labib The investigation and management of obesity J. Clin. Pathol., January 1, 2003; 56(1): 17 - 25. [Abstract] [Full Text] [PDF]

				U. Holmback, A. Forslund, J. Forslund, L. Hambraeus, M. Lennernas, A. Lowden, M. Stridsberg, and T. Akerstedt Metabolic Responses to Nocturnal Eating in Men Are Affected by Sources of Dietary Energy J. Nutr., July 1, 2002; 132(7): 1892 - 1899. [Abstract] [Full Text] [PDF]

				S. Nielsen, J. Levine, R. Clay, and M. D. Jensen Adipose Tissue Metabolism in Benign Symmetric Lipomatosis J. Clin. Endocrinol. Metab., June 1, 2001; 86(6): 2717 - 2720. [Abstract] [Full Text] [PDF]

				S. A. Romanski, R. M. Nelson, and M. D. Jensen Meal fatty acid uptake in human adipose tissue: technical and experimental design issues Am J Physiol Endocrinol Metab, August 1, 2000; 279(2): E447 - E454. [Abstract] [Full Text] [PDF]

				S. A. Romanski, R. M. Nelson, and M. D. Jensen Meal fatty acid uptake in adipose tissue: gender effects in nonobese humans Am J Physiol Endocrinol Metab, August 1, 2000; 279(2): E455 - E462. [Abstract] [Full Text] [PDF]