AJCN Tufts Nutrition Symposium, Boston & Online Sept 2009
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

This Article
Right arrow Full Text (PDF)
Right arrow Purchase Article
Right arrow View Shopping Cart
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Jensen, G. L.
Right arrow Articles by DeMichele, S. J.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Jensen, G. L.
Right arrow Articles by DeMichele, S. J.
Agricola
Right arrow Articles by Jensen, G. L.
Right arrow Articles by DeMichele, S. J.

American Journal of Clinical Nutrition, Vol 60, 518-524, Copyright © 1994 by The American Society for Clinical Nutrition, Inc

ORIGINAL RESEARCH COMMUNICATIONS

Lymphatic absorption of enterally fed structured triacylglycerol vs physical mix in a canine model

GL Jensen, N McGarvey, R Taraszewski, SK Wixson, DL Seidner, T Pai, YY Yeh, TW Lee and SJ DeMichele
Department of Gastroenterology and Nutrition, Geisinger Medical Center, Danville, PA 17822.

The lymphatic absorption of a structured triacylglycerol vs an equivalent physical mixture of the constituent medium-chain triacylglycerol and fish oils was studied. Each of four canines served as its own control in a crossover feeding design with the investigators unaware of diet contents. Lymphatic absorption of n-3 and medium-chain fatty acids peaked within 4-8 h of feeding either diet. The lymph contained more 10:0 fatty acids than 8:0 despite an overall ratio of 10:0 to 8:0 of 0.3 for the diets. The mass of medium-chain fatty acids absorbed in the lymph at measured time points was 2.6 +/- 0.5-fold higher (mean +/- SE of 12 determinations) for the structured triacylglycerol compared with the physical mix. Molecular species analyses revealed that the medium-chain fatty acids in lymph were present as mixed triacylglycerols. The unique molecular structure of these mixed triacylglycerols and the fatty acids at the 2-position may account for the improved absorption.


This article has been cited by other articles:


Home page
 JPEN J Parenter Enteral NutrHome page
Y.-Q. N. You, P.-R. Ling, J. Z. Qu, and B. R. Bistrian
Effects of Medium-Chain Triglycerides, Long-Chain Triglycerides, or 2-Monododecanoin on Fatty Acid Composition in the Portal Vein, Intestinal Lymph, and Systemic Circulation in Rats
JPEN J Parenter Enteral Nutr, March 1, 2008; 32(2): 169 - 175.
[Abstract] [Full Text] [PDF]

Home page
 J. Nutr.Home page
P. Tso, T. Lee, and S. J. DeMichele
Randomized Structured Triglycerides Increase Lymphatic Absorption of Tocopherol and Retinol Compared with the Equivalent Physical Mixture in a Rat Model of Fat Malabsorption
J. Nutr., August 1, 2001; 131(8): 2157 - 2163.
[Abstract] [Full Text] [PDF]

Home page
 Am. J. Physiol. Gastrointest. Liver Physiol.Home page
P. Tso, T. Lee, and S. J. Demichele
Lymphatic absorption of structured triglycerides vs. physical mix in a rat model of fat malabsorption
Am J Physiol Gastrointest Liver Physiol, August 1, 1999; 277(2): G333 - G340.
[Abstract] [Full Text] [PDF]

Home page
 JPEN J Parenter Enteral NutrHome page
W. S. Swails, A. S. Kenler, D. F. Driscoll, S. J. Demichele, T. J. Babineau, T. Utsunamiya, S. Chavali, R. A. Forse, and B. R. Bistrian
Effect of a Fish Oil Structured Lipid-Based Diet on Prostaglandin Release From Mononuclear Cells in Cancer Patients After Surgery
JPEN J Parenter Enteral Nutr, September 1, 1997; 21(5): 266 - 274.
[Abstract] [PDF]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Copyright © 1994 by The American Society for Nutrition