| HOME | HELP | FEEDBACK | SUBSCRIPTIONS | ARCHIVE | SEARCH | TABLE OF CONTENTS |
|
|
|
|||||||
|
|||||||||
American Journal of Clinical Nutrition, Vol 60, 965-968, Copyright © 1994 by The American Society for Clinical Nutrition, Inc
ORIGINAL RESEARCH COMMUNICATIONS |
M Horowitz, JM Wishart, D Goh, HA Morris, AG Need and BE Nordin
Department of Medicine, Royal Adelaide Hospital, Australia.
Calcium supplementation decreases bone resorption and retards bone loss in women. There is little information about the effects of calcium supplementation in men. The effects of a 1-g oral calcium load at 0900 on bone-related biochemical variables were evaluated in 13 normal men (aged 51-70 y). Calcium administration was associated with increases in plasma ionized calcium (P < 0.001) and urinary calcium (P < 0.001), and a decrease in plasma parathyroid hormone (P < 0.001). There was a nonsignificant trend (r = -0.47, P = 0.11) for the decrease in plasma parathyroid hormone to be related to radiocalcium absorption. After the calcium load there were decreases in the urinary hydroxyproline- creatinine ratio from 11 +/- 1.1 to 7.9 +/- 0.6 (P < 0.01), the urinary deoxypyridinoline-creatinine ratio from 14.0 +/- 1.8 to 10.1 +/- 0.9 (P < 0.05), and the urinary pyridinoline-creatinine ratio from 52 +/- 5 to 40 +/- 3 (P < 0.01) between baseline and 6 h. There was no change in plasma osteocalcin. These observations indicate that a 1-g calcium load suppresses biochemical markers of bone resorption for > or = 6 h in normal men and support the concept that calcium supplementation may be useful in the prevention of bone loss in men.
This article has been cited by other articles:
|
|
 |
|
  J. A. Clowes, R. T. Robinson, S. R. Heller, R. Eastell, and A. Blumsohn Acute Changes of Bone Turnover and PTH Induced by Insulin and Glucose: Euglycemic and Hypoglycemic Hyperinsulinemic Clamp Studies J. Clin. Endocrinol. Metab., July 1, 2002; 87(7): 3324 - 3329. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 F. Scopacasa, J.M. Wishart, A.G. Need, M. Horowitz, H.A. Morris, and B.E.C. Nordin Bone Density and Bone-Related Biochemical Variables in Normal Men: A Longitudinal Study J. Gerontol. A Biol. Sci. Med. Sci., June 1, 2002; 57(6): M385 - 391. [Abstract] [Full Text]
|
|
|
|
 |
|
 M. U. Karkkainen, C. J. Lamberg-Allardt, S. Ahonen, and M. Valimaki Does it make a difference how and when you take your calcium? The acute effects of calcium on calcium and bone metabolism Am. J. Clinical Nutrition, September 1, 2001; 74(3): 335 - 342. [Abstract] [Full Text]
|
|
|
|
|
|
M. E. Wastney, B. R. Martin, M. Peacock, D. Smith, X.-Y. Jiang, L. A. Jackman, and C. M. Weaver Changes in Calcium Kinetics in Adolescent Girls Induced by High Calcium Intake J. Clin. Endocrinol. Metab., December 1, 2000; 85(12): 4470 - 4475. [Abstract] [Full Text]
|
|
|
|
|
|
J. Guillemant, H.-T. Le, C. Accarie, S. T. du Montcel, A.-M. Delabroise, M. J Arnaud, and S. Guillemant Mineral water as a source of dietary calcium: acute effects on parathyroid function and bone resorption in young men Am. J. Clinical Nutrition, April 1, 2000; 71(4): 999 - 1002. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 A. Rubinacci, R. Melzi, M. Zampino, A. Soldarini, and I. Villa Total and Free Deoxypyridinoline after Acute Osteoclast Activity Inhibition Clin. Chem., September 1, 1999; 45(9): 1510 - 1516. [Abstract] [Full Text] [PDF]
|
|
| HOME | HELP | FEEDBACK | SUBSCRIPTIONS | ARCHIVE | SEARCH | TABLE OF CONTENTS |
