AJCN Tufts Nutrition Symposium, Boston Sept 24-26
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American Journal of Clinical Nutrition, Vol 61, 1213-1217, Copyright © 1995 by The American Society for Clinical Nutrition, Inc


ORIGINAL RESEARCH COMMUNICATIONS

Dietary fat intake and weight gain in women genetically predisposed for obesity

BL Heitmann, L Lissner, TI Sorensen and C Bengtsson
Danish Epidemiology Science Centre, Institute of Preventive Medicine, Copenhagen.

The influence of dietary fat intake on subsequent change in body mass index (BMI) of adult women was examined while taking into account predisposition for obesity. A representative population sample of 361 Swedish women aged 38-60 y was first examined in 1968-1969 and followed up 6 y later. Dietary intake was estimated by diet history interview, and parental fatness was assessed by questionnaire. Women already overweight with > or = 1 obese parent were considered predisposed to obesity. When total energy intake, smoking habits, physical activity, and menopausal status were controlled for in regression analysis, high dietary fat intake was significantly associated with a 6-y gain in BMI only the predisposed women (P = 0.003), but not among obese women with lean parents, or lean women with or without obese parents. High dietary fat intake may have an obesity-promoting effect in women with a genetic predisposition.


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