AJCN Cancer Health Disparities Conference
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

This Article
Right arrow Full Text (PDF)
Right arrow Purchase Article
Right arrow View Shopping Cart
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Golub, M. S.
Right arrow Articles by Hendrickx, A. G.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Golub, M. S.
Right arrow Articles by Hendrickx, A. G.
Agricola
Right arrow Articles by Golub, M. S.
Right arrow Articles by Hendrickx, A. G.

American Journal of Clinical Nutrition, Vol 64, 274-282, Copyright © 1996 by The American Society for Clinical Nutrition, Inc

ORIGINAL RESEARCH COMMUNICATIONS

Adolescent growth and maturation in zinc-deprived rhesus monkeys [see comment]

MS Golub, CL Keen, ME Gershwin, DM Styne, PT Takeuchi, F Ontell, RM Walter and AG Hendrickx
Department of Internal Medicine, University of California, Davis 95616, USA. msgolub@ucdavis.edu

Growth retardation has been associated with zinc deficiency in adolescent human populations, but animal models were not available previously to explore this syndrome. Moderate dietary zinc deprivation (2 micrograms Zn/g diet) was introduced in female rhesus monkeys (Macaca mulatta; n = 10) from the beginning of puberty through menarche. Subgroups of animals (n = 4) continued to be fed the zinc- deficient diet through 45 mo of age (sexual maturity). Reduced weight gain and linear growth and lower plasma zinc concentrations (11.8 +/- 0.6 and 9.2 +/- 0.8 mumol/L in control and zinc-deficient monkeys, respectively) were evident during the premenarcheal growth spurt. Slower skeletal growth, maturation, and mineralization were recorded in the postmenarcheal period and some indicators of sexual maturation were delayed. Food intake was slightly higher in the zinc-deficient group than in controls. These data confirm that adolescent growth and maturation are vulnerable to disruption by moderate dietary zinc deprivation in nonhuman primates.


This article has been cited by other articles:


Home page
 Am. J. Clin. Nutr.Home page
M J. Heinig, K. H Brown, B. Lonnerdal, and K. G Dewey
Zinc supplementation does not affect growth, morbidity, or motor development of US term breastfed infants at 4-10 mo of age.
Am. J. Clinical Nutrition, September 1, 2006; 84(3): 594 - 601.
[Abstract] [Full Text] [PDF]

Home page
 J Trop PediatrHome page
A. A.-B. Rwebembera, E. K. D. Munubhi, K. P. Manji, R. Mpembeni, and J. Philip
Relationship Between Infant Birth Weight <=2000 g and Maternal Zinc Levels at Muhimbili National Hospital, Dar Es Salaam, Tanzania
J Trop Pediatr, April 1, 2006; 52(2): 118 - 125.
[Abstract] [Full Text] [PDF]

Home page
 Am. J. Clin. Nutr.Home page
B. S Zemel, D. A Kawchak, E. B Fung, K. Ohene-Frempong, and V. A Stallings
Effect of zinc supplementation on growth and body composition in children with sickle cell disease
Am. J. Clinical Nutrition, February 1, 2002; 75(2): 300 - 307.
[Abstract] [Full Text] [PDF]

Home page
 Am. J. Clin. Nutr.Home page
M. S Golub, C. L Keen, and M E. Gershwin
Behavioral and hematologic consequences of marginal iron-zinc nutrition in adolescent monkeys and the effect of a powdered beef supplement
Am. J. Clinical Nutrition, December 1, 1999; 70(6): 1059 - 1068.
[Abstract] [Full Text] [PDF]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Copyright © 1996 by The American Society for Nutrition