American Journal of Clinical Nutrition, Vol 65, 1410-1418, Copyright © 1997 by The American Society for Clinical Nutrition, Inc

ORIGINAL RESEARCH COMMUNICATIONS

Satiety power of dietary fat: a new appraisal

A Himaya, M Fantino, JM Antoine, L Brondel and J Louis-Sylvestre
Laboratoire de Neurobiologie de la Nutrition, Ecole Pratique des Hautes Etudes, Paris, France.

Accumulating evidence suggest that a good way to compare the satiety power of meals with different compositions or energy contents is to measure the onset latency of the next meal when freely requested by subjects deprived of any time cues. This study was performed in normal- weight young men (aged 19-24 y) isolated from time cues. At sessions 1 and 2, we studied the effects of two high-carbohydrate pasta lunchs with either 50 g low-energy butter substitute (lunch A) or 50 g butter (lunch B) on hunger ratings, on the latency of the dinner request, and on energy and nutrient intakes at the offered ad libitum dinner. Sessions 3 and 4 were designed to examine the effects of the two lunchs on the postlunch and predinner profiles of plasma glucose, insulin, glucagon, and lipids; consequences on the metabolic and hormonal responses to the fixed dinner offered on request also were tested. The addition of 1588 kJ butter to the pasta lunch compared with the addition of 67 kJ butter substitute had no effect on hunger ratings but significantly delayed the onset of dinner by approximately 38 min; however, neither energy intake nor nutrient intakes were different. The high-fat lunch led to a slightly different postlunch plasma glucose concentration profile but, as expected, to higher plasma triacylglycerol and fatty acid concentrations. The high-fat lunch also led to postdinner glucose intolerance with normal insulin and high fatty acid concentrations that may help explain the partial and delayed adjustment in energy intake after a high-fat meal as reported by some studies.

This article has been cited by other articles:

				A. J A H van Vught, A. G Nieuwenhuizen, R.-J. M Brummer, and M. S Westerterp-Plantenga Somatotropic responses to soy protein alone and as part of a meal. Eur. J. Endocrinol., July 1, 2008; 159(1): 15 - 18. [Abstract] [Full Text] [PDF]

				S. F. Leibowitz, G.-Q. Chang, J. T. Dourmashkin, R. Yun, C. Julien, and P. P. Pamy Leptin secretion after a high-fat meal in normal-weight rats: strong predictor of long-term body fat accrual on a high-fat diet Am J Physiol Endocrinol Metab, February 1, 2006; 290(2): E258 - E267. [Abstract] [Full Text] [PDF]

				D. E. Cummings, R. S. Frayo, C. Marmonier, R. Aubert, and D. Chapelot Plasma ghrelin levels and hunger scores in humans initiating meals voluntarily without time- and food-related cues Am J Physiol Endocrinol Metab, August 1, 2004; 287(2): E297 - E304. [Abstract] [Full Text] [PDF]

				C. Marmonier, D. Chapelot, M. Fantino, and J. Louis-Sylvestre Snacks consumed in a nonhungry state have poor satiating efficiency: influence of snack composition on substrate utilization and hunger Am. J. Clinical Nutrition, September 1, 2002; 76(3): 518 - 528. [Abstract] [Full Text] [PDF]

				V. Van Wymelbeke, J. Louis-Sylvestre, and M. Fantino Substrate oxidation and control of food intake in men after a fat-substitute meal compared with meals supplemented with an isoenergetic load of carbohydrate, long-chain triacylglycerols, or medium-chain triacylglycerols Am. J. Clinical Nutrition, November 1, 2001; 74(5): 620 - 630. [Abstract] [Full Text] [PDF]

				D. Chapelot, R. Aubert, C. Marmonier, M. Chabert, and J. Louis-Sylvestre An endocrine and metabolic definition of the intermeal interval in humans: evidence for a role of leptin on the prandial pattern through fatty acid disposal Am. J. Clinical Nutrition, August 1, 2000; 72(2): 421 - 431. [Abstract] [Full Text] [PDF]

				C. Marmonier, D. Chapelot, and J. Louis-Sylvestre Metabolic and behavioral consequences of a snack consumed in a satiety state Am. J. Clinical Nutrition, November 1, 1999; 70(5): 854 - 866. [Abstract] [Full Text] [PDF]

				K. J. Melanson, M. S. Westerterp-Plantenga, W. H. M. Saris, F. J. Smith, and L. A. Campfield Blood glucose patterns and appetite in time-blinded humans: carbohydrate versus fat Am J Physiol Regulatory Integrative Comp Physiol, August 1, 1999; 277(2): R337 - R345. [Abstract] [Full Text] [PDF]