HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS		QUICK SEARCH:   [advanced] Author: Keyword(s): Year:  Vol:  Page:

This Article Full Text Full Text (PDF) Purchase Article View Shopping Cart Alert me when this article is cited Alert me if a correction is posted Citation Map Services Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via HighWire Citing Articles via Google Scholar Google Scholar Articles by White, M. D Articles by Jones, P. J. Search for Related Content PubMed PubMed Citation Articles by White, M. D Articles by Jones, P. J. Agricola Articles by White, M. D Articles by Jones, P. J.

Enhanced postprandial energy expenditure with medium-chain fatty acid feeding is attenuated after 14 d in premenopausal women^1,2,3

Background: Medium-chain triacylglycerols (MCTs) are reported to enhance human energy expenditure (EE), although few studies have involved women and the duration of such effects is only known for periods of 7 d.

Objective: This study was conducted to determine whether women consuming mixed, MCT-enriched or long-chain triacylglycerol (LCT)–enriched diets showed changes in EE or substrate oxidation after 7 and 14 d.

Design: Twelve nonobese, premenopausal women were fed isoenergetic mixed diets enriched in either MCTs or LCTs during separate, 14-d feeding periods. Each meal contained 40% of energy as fat (80% of which was the treatment fat), 45% as carbohydrate, and 15% as protein. On days 7 and 14 of each trial, basal metabolic rate (BMR, kJ/min), total energy expenditure (TEE, kJ/min), and thermic effect of feeding (kJ/min) after a standardized breakfast were measured by respiratory gas exchange.

Results: On day 7, the mean (±SEM) BMR (3.58 ± 0.11 kJ/min) with the MCT diet was greater (P = 0.0003) than that with the LCT diet (3.43 ± 0.11 kJ/min). The mean postprandial TEE on day 7 was significantly greater (P = 0.04) with the MCT diet (4.36 ± 0.04 kJ/min) than with the LCT diet (4.23 ± 0.04 kJ/min); by day 14, postprandial TEE was still greater with the MCT diet, but not significantly so. No significant differences in the thermic effect of feeding were evident between diets.

Conclusions: Results from this longest controlled MCT feeding study to date suggest that short-term feeding of MCT-enriched diets increases TEE, but this effect could be transient with continued feeding.

Key Words: Premenopausal women • medium-chain triacylglycerols • long-chain triacylglycerols • thermic effect of food • respiratory quotient • fat oxidation • carbohydrate oxidation • energy expenditure

This article has been cited by other articles:

				M.-P. St-Onge and A. Bosarge Weight-loss diet that includes consumption of medium-chain triacylglycerol oil leads to a greater rate of weight and fat mass loss than does olive oil Am. J. Clinical Nutrition, March 1, 2008; 87(3): 621 - 626. [Abstract] [Full Text] [PDF]

				N. R. Stob, C. Bell, M. A. van Baak, and D. R. Seals Thermic effect of food and beta-adrenergic thermogenic responsiveness in habitually exercising and sedentary healthy adult humans J Appl Physiol, August 1, 2007; 103(2): 616 - 622. [Abstract] [Full Text] [PDF]

				M.-P. St-Onge, B. Lamarche, J.-F. Mauger, and P. J. H. Jones Consumption of a Functional Oil Rich in Phytosterols and Medium-Chain Triglyceride Oil Improves Plasma Lipid Profiles in Men J. Nutr., June 1, 2003; 133(6): 1815 - 1820. [Abstract] [Full Text] [PDF]

				M.-P. St-Onge and P. J. H. Jones Physiological Effects of Medium-Chain Triglycerides: Potential Agents in the Prevention of Obesity J. Nutr., March 1, 2002; 132(3): 329 - 332. [Abstract] [Full Text] [PDF]

				H. Bendixen, A. Flint, A. Raben, C.-E. Hoy, H. Mu, X. Xu, E. M. Bartels, and A. Astrup Effect of 3 modified fats and a conventional fat on appetite, energy intake, energy expenditure, and substrate oxidation in healthy men Am. J. Clinical Nutrition, January 1, 2002; 75(1): 47 - 56. [Abstract] [Full Text] [PDF]