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American Journal of Clinical Nutrition, Vol 7, 43-49, Copyright © 1959 by The American Society for Clinical Nutrition, Inc.

Metabolic Effect of Fat Emulsion

WILLIAM R. WADDELL M.D.1 and HERMES C. GRILLO M.D.1

1 From the Department of Nutrition, Harvard School of Public Health; the Department of Surgery, Harvard Medical School; and the Surgical Service, Massachusetts General Hospital, Boston, Massachusetts

The effect of intravenous fat emulsion on nitrogen, potassium, sodium, and chloride metabolism was studied in four subjects, using the balance technic. It is concluded that fat emulsion promotes nitrogen and potassium retention in some patients, but that in other patients administration of fat emulsion under similar circumstances may be associated with excess nitrogen losses. Comparison of oral and intravenous feeding failed to demonstrate any difference in nitrogen metabolism, and it is concluded that the two methods are equivalent. Attention is directed to the fact that sodium and chloride retention may be associated with administration of intravenous fat.







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Copyright © 1959 by The American Society for Nutrition