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American Journal of Clinical Nutrition, Vol 7, 206-212, Copyright © 1959 by The American Society for Clinical Nutrition, Inc.

The Peroxide-Erythrocyte Hemolysis Test

Experiences in Patients with Cirrhosis, Jaundice, and Polyneuritis

JAMES M. STORMONT M.D.1, ELAINE A. HIRSHBERG B.S.1, and CHARLES S. DAVIDSON M.D.1

1 From the Thorndike Memorial Laboratory and Second and Fourth (Harvard) Medical Services, Boston City Hospital, and the Department of Medicine, Harvard Medical School, Boston, Mass.

Red blood cell sensitivity to hemolysis with hydrogen peroxide has been determined in 52 patients, 49 of whom had cirrhosis.

No definite correlation was found with the severity of cirrhosis, the presence of jaundice, or the presence of "alcoholic hyalin" and necrosis of the liver.

Only two patients had strongly positive tests (greater than 50 per cent hemolysis), and both had multivitamin deficiency with mild cirrhosis and severe polyneuropathy suggesting but not proving vitamin E deficiency in these two patients.






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Copyright © 1959 by The American Society for Nutrition