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American Journal of Clinical Nutrition, Vol 7, 325-327, Copyright © 1959 by The American Society for Clinical Nutrition, Inc.

Effect of d-Sorbitol on Absorption of Vitamin B12 by Human Subjects Able To Produce Intrinsic Factor

VICTOR HERBERT M.D.1, MARTIN BIERFASS M.D.1, LOUIS R. WASSERMAN M.D.1, SOLOMON ESTREN M.D.1, and EUGENE BRODY M.D.1

1 From the Department of Hematology, The Mount Sinai Hospital, New York, New York

d-sorbitol may enhance the absorption of supraphysiologic (30 µg) and in some cases physiologic (2 µg) oral doses of vitamin B12 in individuals whose ability to secrete intrinsic factor is normal. Any therapeutic utility of this agent in terms of enhancing vitamin B12 absorption remains questionable.






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Copyright © 1959 by The American Society for Nutrition