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1 From the Division of Physiology and Metabolism, Department of Nutrition Sciences, University of Alabama at Birmingham.
This review examines whether the relations and metabolic parameters necessary for the development of syndrome X are present in children and whether the metabolic complications of obesity in children are explained by excess intraabdominal adipose tissue (IAAT), or visceral fat. Despite the limited use of imaging techniques in research studies, an increasing number of studies reported on IAAT and its relation to disease risk in children and adolescents. For this article we reviewed studies that documented the early accumulation of IAAT in children and adolescents and the factors that contribute to variation in the degree of IAAT accumulation. We also reviewed studies that showed the clinical relevance of IAAT in children and adolescents through significant relations with adverse health effects including dyslipidemia and glucose intolerance in obese and nonobese children and adolescents of different ethnic groups.
Key Words: Fat distribution visceral fat subcutaneous fat intraabdominal adipose tissue subcutaneous abdominal adipose tissue diabetes cardiovascular disease heart disease dyslipidemia obesity development metabolic risk disease risk children adolescents ethnicity syndrome X
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