| HOME | HELP | FEEDBACK | SUBSCRIPTIONS | ARCHIVE | SEARCH | TABLE OF CONTENTS |
|
|
|
|||||||
|
|||||||||
Supplements |
1 From the Section of Clinical Nutrition and Lipid Metabolism, Department of Medicine, Oregon Health Sciences University, Portland, and the Division of Neuroscience, Oregon Regional Primate Research Center, Beaverton.
Animal and human studies have documented several effects of different dietary and tissue concentrations of long-chain polyunsaturated fatty acids (LCPUFAs) on retinal function and vision. The enhanced visual development associated with increased intakes of LCPUFAs, particularly docosahexaenoic acid (DHA), provides the strongest evidence for the importance of these fatty acids in infant nutrition. The 2 primary visual measures used to assess the efficacy of infant formula LCPUFA supplementation are the electroretinogram and visual acuity. This review briefly describes the methodology, neural basis, and interpretation of these measures, as well as other measures of visual development that may be used to extend the functional evaluation of infants fed formulas with different fatty acid compositions.
Key Words: Infant nutrition • n–3 fatty acids • docosahexaenoic acid • long-chain polyunsaturated fatty acids • visual development • visual acuity • retina • electroretinogram
This article has been cited by other articles:
|
|
 |
|
  J. C McCann and B. N Ames Is docosahexaenoic acid, an n-3 long-chain polyunsaturated fatty acid, required for development of normal brain function? An overview of evidence from cognitive and behavioral tests in humans and animals Am. J. Clinical Nutrition, August 1, 2005; 82(2): 281 - 295. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 K. M. Heinemann, M. K. Waldron, K. E. Bigley, G. E. Lees, and J. E. Bauer Long-Chain (n-3) Polyunsaturated Fatty Acids Are More Efficient than {alpha}-Linolenic Acid in Improving Electroretinogram Responses of Puppies Exposed during Gestation, Lactation, and Weaning J. Nutr., August 1, 2005; 135(8): 1960 - 1966. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
D. R. Hoffman, R. C. Theuer, Y. S. Castaneda, D. H. Wheaton, R. G. Bosworth, A. R. O'Connor, S. E. Morale, L. E. Wiedemann, and E. E. Birch Maturation of Visual Acuity Is Accelerated in Breast-Fed Term Infants Fed Baby Food Containing DHA-Enriched Egg Yolk J. Nutr., September 1, 2004; 134(9): 2307 - 2313. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 T. Huber, A. V. Botelho, K. Beyer, and M. F. Brown Membrane Model for the G-Protein-Coupled Receptor Rhodopsin: Hydrophobic Interface and Dynamical Structure Biophys. J., April 1, 2004; 86(4): 2078 - 2100. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 G.-Y. Diau, E. R. Loew, V. Wijendran, E. Sarkadi-Nagy, P. W. Nathanielsz, and J. T. Brenna Docosahexaenoic and Arachidonic Acid Influence on Preterm Baboon Retinal Composition and Function Invest. Ophthalmol. Vis. Sci., October 1, 2003; 44(10): 4559 - 4566. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 A Hommer, B Kapik, and N Shams Unoprostone as adjunctive therapy to timolol: a double masked randomised study versus brimonidine and dorzolamide Br. J. Ophthalmol., May 1, 2003; 87(5): 592 - 598. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
S. R Cheruku, H. E Montgomery-Downs, S. L Farkas, E. B Thoman, and C. J Lammi-Keefe Higher maternal plasma docosahexaenoic acid during pregnancy is associated with more mature neonatal sleep-state patterning Am. J. Clinical Nutrition, September 1, 2002; 76(3): 608 - 613. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 D. C. Mitchell, S.-L. Niu, and B. J. Litman Optimization of Receptor-G Protein Coupling by Bilayer Lipid Composition I. KINETICS OF RHODOPSIN-TRANSDUCIN BINDING J. Biol. Chem., November 9, 2001; 276(46): 42801 - 42806. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
S. E Carlson Behavioral methods used in the study of long-chain polyunsaturated fatty acid nutrition in primate infants1 Am. J. Clinical Nutrition, January 1, 2000; 71(1): 268S - 274S. [Abstract] [Full Text] [PDF]
|
|
| HOME | HELP | FEEDBACK | SUBSCRIPTIONS | ARCHIVE | SEARCH | TABLE OF CONTENTS |
