| HOME | HELP | FEEDBACK | SUBSCRIPTIONS | ARCHIVE | SEARCH | TABLE OF CONTENTS |
|
|
|
|||||||
|
|||||||||
Supplements |
1 From the Department of Neonatology and Human's Nutrition Center, Hôpital Edouard Herriot, Lyon, France; the Laboratory of Biochemistry, Sainte Justine Hospital, Montréal; the Division of Child Health, University of Sheffield, Sheffield Children's Hospital, Sheffield, United Kingdom; and the Genetics Unit, Shriners Hospital for Children , Montréal.
During pregnancy, maternal serum concentrations of 25-hydroxyvitamin D, the circulating form of vitamin D, correlate with dietary vitamin D intake. Maternal serum concentrations of 1,25-dihydroxyvitamin D, the hormonal circulating and active form of vitamin D, are elevated during pregnancy; 1,25-dihydroxyvitamin D is synthesized mainly by the decidual cells of the placenta and allows for increased calcium absorption. The fetus is entirely dependent on the mother for its supply of 25-hydroxyvitamin D, which is believed to cross the placenta. Hypocalcemia and increased parathyroid hormone secretion induce synthesis of 1,25-dihydroxyvitamin D after birth in both full-term and preterm neonates. Nevertheless, serum concentrations of 25-hydroxyvitamin D are a rate-limiting factor in the synthesis of 1,25-dihydroxyvitamin D. In vitamin D–replete infants, circulating 1,25-dihydroxyvitamin D concentrations are higher than those observed in older infants. In countries where dairy products are not routinely supplemented with vitamin D, maternal vitamin D supplementation during pregnancy is necessary. However, there is no indication for the use of pharmacologic doses of vitamin D or its metabolites in the perinatal period.
Key Words: 25-Hydroxyvitamin D • 1,25-dihydroxyvitamin D • mineral metabolism • parathyroid hormone • pregnancy • preterm infant • term infant
This article has been cited by other articles:
|
|
 |
|
  S H Dijkstra, A van Beek, J W Janssen, L H M de Vleeschouwer, W A Huysman, and E L T van den Akker High prevalence of vitamin D deficiency in newborn infants of high-risk mothers Arch. Dis. Child., September 1, 2007; 92(9): 750 - 753. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 S. A Abrams In utero physiology: role in nutrient delivery and fetal development for calcium, phosphorus, and vitamin D Am. J. Clinical Nutrition, February 1, 2007; 85(2): 604S - 607S. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
I. M van der Meer, N. S Karamali, A J. P Boeke, P. Lips, B. J. Middelkoop, I. Verhoeven, and J. D Wuister High prevalence of vitamin D deficiency in pregnant non-Western women in The Hague, Netherlands. Am. J. Clinical Nutrition, August 1, 2006; 84(2): 350 - 353. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 P Vigano, D Lattuada, S Mangioni, L Ermellino, M Vignali, E Caporizzo, P Panina-Bordignon, M Besozzi, and A M Di Blasio Cycling and early pregnant endometrium as a site of regulated expression of the vitamin D system. J. Mol. Endocrinol., June 1, 2006; 36(3): 415 - 424. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 A. Alikasifoglu, E. N. Gonc, E. Yalcin, D. Dogru, and N. Yordam Neonatal Hyperparathyroidism Due to Maternal Hypoparathyroidism and Vitamin D Deficiency: A Cause of Multiple Bone Fractures Clinical Pediatrics, April 1, 2005; 44(3): 267 - 269. [PDF]
|
|
|
|
|
|
A. Lapillonne, B. L Salle, F. H Glorieux, and O. Claris Bone mineralization and growth are enhanced in preterm infants fed an isocaloric, nutrient-enriched preterm formula through term Am. J. Clinical Nutrition, December 1, 2004; 80(6): 1595 - 1603. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
N. Pawley and N. J Bishop Prenatal and infant predictors of bone health: the influence of vitamin D Am. J. Clinical Nutrition, December 1, 2004; 80(6): 1748S - 1751S. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 A. Prentice Micronutrients and the Bone Mineral Content of the Mother, Fetus and Newborn J. Nutr., May 1, 2003; 133(5): 1693S - 1699. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 A. Lapillonne, R. Travers, M. DiMaio, B. L. Salle, and F. H. Glorieux Urinary Excretion of Cross-Linked N-Telopeptides of Type 1 Collagen to Assess Bone Resorption in Infants From Birth to 1 Year of Age Pediatrics, July 1, 2002; 110(1): 105 - 109. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 W. R. Waters, B. J. Nonnecke, T. E. Rahner, M. V. Palmer, D. L. Whipple, and R. L. Horst Modulation of Mycobacterium bovis-Specific Responses of Bovine Peripheral Blood Mononuclear Cells by 1,25-Dihydroxyvitamin D3 Clin. Vaccine Immunol., November 1, 2001; 8(6): 1204 - 1212. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
K. M. Tomashek, S. Nesby, K. S. Scanlon, M. E. Cogswell, K. E. Powell, U. D. Parashar, A. Mellinger-Birdsong, L. M. Grummer-Strawn, and W. H. Dietz COMMENTARY: Nutritional Rickets in Georgia Pediatrics, April 1, 2001; 107(4): e45 - e45. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
A. Prentice Maternal calcium metabolism and bone mineral status Am. J. Clinical Nutrition, May 1, 2000; 71(5): 1312S - 1316. [Abstract] [Full Text] [PDF]
|
|
| HOME | HELP | FEEDBACK | SUBSCRIPTIONS | ARCHIVE | SEARCH | TABLE OF CONTENTS |
