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American Journal of Clinical Nutrition, Vol. 73, No. 2, 361S-364s, February 2001
© 2001 American Society for Clinical Nutrition


Supplement

Probiotics, prebiotics, and synbiotics—approaching a definition1,2,3

Jürgen Schrezenmeir and Michael de Vrese

1 From the Institute of Physiology and Biochemistry of Nutrition, Federal Dairy Research Center, Kiel, Germany.

Definitions of different pro-, pre-, and synbiotics suggested by different investigators are critically discussed. On the basis of this analysis, the probiotic concept is confined to effects exerted by viable microorganisms but is applicable independent of the site of action and route of administration. It therefore may include sites such as the oral cavity, the intestine, the vagina, and the skin.

Key Words: Probiotic • prebiotic • synbiotic • health claims • definitions • history




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