AJCN Cancer Health Disparities Conference
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

This Article
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow Purchase Article
Right arrow View Shopping Cart
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Right arrow Citation Map
Services
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Jones, G.
Right arrow Articles by Whiting, S.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Jones, G.
Right arrow Articles by Whiting, S.
Agricola
Right arrow Articles by Jones, G.
Right arrow Articles by Whiting, S.
American Journal of Clinical Nutrition, Vol. 73, No. 4, 839-844, April 2001
© 2001 American Society for Clinical Nutrition

ORIGINAL RESEARCH COMMUNICATIONS

Association between urinary potassium, urinary sodium, current diet, and bone density in prepubertal children1,2,3

Graeme Jones, Malcolm D Riley and Susan Whiting

1 From the Menzies Centre for Population Health Research, Hobart, Australia, and the College of Pharmacy and Nutrition, University of Saskatchewan, Saskatoon, Canada.

Background: Our understanding of the role of nutrients in bone development in children is limited.

Objective: We examined the associations between urinary potassium, urinary sodium, usual dietary intake, and bone mineral density (BMD) in prepubertal children.

Design: This was a cross-sectional study of 330 boys and girls aged 8 y. Urinary measures were assessed in a single, timed, overnight urine specimen. Usual diet was assessed with a food-frequency questionnaire completed by a parent or guardian. BMD at the femoral neck, lumbar spine, and total body was measured by dual-energy X-ray absorptiometry.

Results: Urinary potassium correlated significantly with BMD at all sites (femoral neck: r = 0.20, P < 0.001; lumbar spine: r = 0.19, P = 0.001; total body: r = 0.24, P < 0.001). After adjustment for confounders (primarily lean body mass), this association was lower in magnitude but remained significant at 2 sites with a consistent trend at the third (femoral neck: P = 0.15; lumbar spine: P = 0.046; total body: P = 0.028). Urinary sodium was not associated with BMD at any site. No nutrient or food intake estimate was associated with BMD, although urinary potassium correlated significantly with potassium intake (r = 0.14, P = 0.016) and fruit and vegetable intake (r = 0.12, P = 0.033).

Conclusions: Urinary potassium was associated with both dietary intake and BMD independent of lean body mass in these well-nourished, calcium-replete young children. These findings should be confirmed in further longitudinal studies. Nevertheless, this association is likely to represent dietary intake of potassium and suggests that measurement of urinary potassium is superior to food-frequency questionnaires for assessing potassium intake in this age group.

Key Words: Bone mineral density • urinary potassium • prepubertal children • dietary intake • urinary sodium • food-frequency questionnaire




This article has been cited by other articles:


Home page
 Am. J. Clin. Nutr.Home page
T. R Fenton, M. Eliasziw, A. W Lyon, S. C Tough, and D. A Hanley
Meta-analysis of the quantity of calcium excretion associated with the net acid excretion of the modern diet under the acid-ash diet hypothesis
Am. J. Clinical Nutrition, October 1, 2008; 88(4): 1159 - 1166.
[Abstract] [Full Text] [PDF]

Home page
 J. Nutr.Home page
S. A. Lanham-New
The Balance of Bone Health: Tipping the Scales in Favor of Potassium-Rich, Bicarbonate-Rich Foods
J. Nutr., January 1, 2008; 138(1): 172S - 177S.
[Abstract] [Full Text] [PDF]

Home page
 BMJHome page
T. Winzenberg, K. Shaw, J. Fryer, and G. Jones
Effects of calcium supplementation on bone density in healthy children: meta-analysis of randomised controlled trials
BMJ, October 14, 2006; 333(7572): 775.
[Abstract] [Full Text] [PDF]

Home page
 Am. J. Clin. Nutr.Home page
S. A Lanham-New
Fruit and vegetables: the unexpected natural answer to the question of osteoporosis prevention?
Am. J. Clinical Nutrition, June 1, 2006; 83(6): 1254 - 1255.
[Full Text] [PDF]

Home page
 Am. J. Clin. Nutr.Home page
H. Vatanparast, A. Baxter-Jones, R. A Faulkner, D. A Bailey, and S. J Whiting
Positive effects of vegetable and fruit consumption and calcium intake on bone mineral accrual in boys during growth from childhood to adolescence: the University of Saskatchewan Pediatric Bone Mineral Accrual Study
Am. J. Clinical Nutrition, September 1, 2005; 82(3): 700 - 706.
[Abstract] [Full Text] [PDF]

Home page
 J. Am. Coll. Nutr.Home page
K. Rafferty, K. M. Davies, and R. P. Heaney
Potassium Intake and the Calcium Economy
J. Am. Coll. Nutr., April 1, 2005; 24(2): 99 - 106.
[Abstract] [Full Text] [PDF]

Home page
 PediatricsHome page
A. J. Lanou, S. E. Berkow, and N. D. Barnard
Calcium, Dairy Products, and Bone Health in Children and Young Adults: A Reevaluation of the Evidence
Pediatrics, March 1, 2005; 115(3): 736 - 743.
[Abstract] [Full Text] [PDF]

Home page
 J. Nutr.Home page
C. Demigne, H. Sabboh, C. Remesy, and P. Meneton
Protective Effects of High Dietary Potassium: Nutritional and Metabolic Aspects
J. Nutr., November 1, 2004; 134(11): 2903 - 2906.
[Abstract] [Full Text] [PDF]

Home page
 Am. J. Clin. Nutr.Home page
S. R Zwart, A. R Hargens, and S. M Smith
The ratio of animal protein intake to potassium intake is a predictor of bone resorption in space flight analogues and in ambulatory subjects
Am. J. Clinical Nutrition, October 1, 2004; 80(4): 1058 - 1065.
[Abstract] [Full Text] [PDF]

Home page
 Arch Pediatr Adolesc MedHome page
C. J. Chantry, P. Auinger, and R. S. Byrd
Lactation Among Adolescent Mothers and Subsequent Bone Mineral Density
Arch Pediatr Adolesc Med, July 1, 2004; 158(7): 650 - 656.
[Abstract] [Full Text]

Home page
 J. Nutr.Home page
S. J. Whiting, H. Vatanparast, A. Baxter-Jones, R. A. Faulkner, R. Mirwald, and D. A. Bailey
Factors that Affect Bone Mineral Accrual in the Adolescent Growth Spurt
J. Nutr., March 1, 2004; 134(3): 696S - 700.
[Abstract] [Full Text] [PDF]

Home page
 Am. J. Clin. Nutr.Home page
F. A Tylavsky, K. Holliday, R. Danish, C. Womack, J. Norwood, and L. Carbone
Fruit and vegetable intakes are an independent predictor of bone size in early pubertal children
Am. J. Clinical Nutrition, February 1, 2004; 79(2): 311 - 317.
[Abstract] [Full Text] [PDF]

Home page
 J. Nutr.Home page
K. S. Krogholm, J. Haraldsdottir, P. Knuthsen, and S. E. Rasmussen
Urinary Total Flavonoid Excretion but Not 4-Pyridoxic Acid or Potassium Can Be Used as a Biomarker for the Intake of Fruits and Vegetables
J. Nutr., February 1, 2004; 134(2): 445 - 451.
[Abstract] [Full Text] [PDF]

Home page
 Am. J. Clin. Nutr.Home page
S. A New, H. M MacDonald, M. K Campbell, J. C Martin, M. J Garton, S. P Robins, and D. M Reid
Lower estimates of net endogenous noncarbonic acid production are positively associated with indexes of bone health in premenopausal and perimenopausal women
Am. J. Clinical Nutrition, January 1, 2004; 79(1): 131 - 138.
[Abstract] [Full Text] [PDF]

Home page
 J. Nutr.Home page
P.-H. Lin, F. Ginty, L. J. Appel, M. Aickin, A. Bohannon, P. Garnero, D. Barclay, and L. P. Svetkey
The DASH Diet and Sodium Reduction Improve Markers of Bone Turnover and Calcium Metabolism in Adults
J. Nutr., October 1, 2003; 133(10): 3130 - 3136.
[Abstract] [Full Text] [PDF]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Copyright © 2001 by The American Society for Nutrition