| HOME | HELP | FEEDBACK | SUBSCRIPTIONS | ARCHIVE | SEARCH | TABLE OF CONTENTS |
|
|
|
|||||||
|
|||||||||
Original Research Communication |
1 From the Human Nutrition Research Center on Aging, Tufts University, Boston; the National Cancer Institute, Divisions of Cancer Epidemiology and Genetics and of Cancer Control and Population Sciences, Bethesda, MD; and the University of Nebraska Medical Center, Department of Pathology and Microbiology, Omaha.
Background: Dietary pattern analysis is a unique approach to studying relations between diet and disease.
Objective: Our objective was to describe the dietary patterns of an eastern Nebraska population and investigate the associations between those dietary patterns and risks of adenocarcinoma of the esophagus and distal stomach.
Design: We recruited 124 subjects with esophageal adenocarcinoma, 124 subjects with distal stomach adenocarcinoma, and 449 control subjects in a population-based, case-control study.
Results: Six dietary patterns were identified with the use of cluster analysis. The first dietary pattern represented healthy food choices and had higher energy contributions from fruit and vegetables and grain products and lower energy contributions from red meats, processed meats, and gravy than did the other dietary patterns. In contrast, a second dietary pattern was high in meats and low in fruit and cereals. The other 4 dietary patterns were each characterized by a concentrated energy source: salty snacks, desserts, milk, and white bread, respectively. The test of overall difference in cancer risk across dietary patterns was significant for distal stomach adenocarcinoma (P = 0.04) but not for esophageal adenocarcinoma. Risk of esophageal adenocarcinoma was inversely associated with intakes of dairy products, fish, all vegetables, citrus fruit and juices, and dark bread and was positively associated with gravy intake. Risk of distal stomach adenocarcinoma was positively associated with red meat intake.
Conclusions: Our study suggests that a diet high in fruit and vegetables may decrease the risk of esophageal adenocarcinoma and that a diet high in meats may increase the risk of distal stomach adenocarcinoma.
Key Words: Esophagus • stomach • neoplasm • dietary pattern • cluster analysis • cancer
This article has been cited by other articles:
|
|
 |
|
  V. Edefonti, G. Randi, A. Decarli, C. La Vecchia, C. Bosetti, S. Franceschi, L. Dal Maso, and M. Ferraroni Clustering dietary habits and the risk of breast and ovarian cancers Ann. Onc., October 7, 2008; (2008) mdn594v1. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 S. P Mehta, A. P Boddy, J. Cook, V. Sams, E. K Lund, I. T Johnson, and M. Rhodes Effect of n-3 polyunsaturated fatty acids on Barrett's epithelium in the human lower esophagus Am. J. Clinical Nutrition, April 1, 2008; 87(4): 949 - 956. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 P. T. Campbell, M. Sloan, and N. Kreiger Dietary Patterns and Risk of Incident Gastric Adenocarcinoma Am. J. Epidemiol., February 1, 2008; 167(3): 295 - 304. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 G. L. Austin, L. S. Adair, J. A. Galanko, C. F. Martin, J. A. Satia, and R. S. Sandler A Diet High in Fruits and Low in Meats Reduces the Risk of Colorectal Adenomas J. Nutr., April 1, 2007; 137(4): 999 - 1004. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
J. L Hutton, L. Martin, C. J Field, W. V Wismer, E. D Bruera, S. M Watanabe, and V. E Baracos Dietary patterns in patients with advanced cancer: implications for anorexia-cachexia therapy. Am. J. Clinical Nutrition, November 1, 2006; 84(5): 1163 - 1170. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 S. C. Larsson, N. Orsini, and A. Wolk Processed meat consumption and stomach cancer risk: a meta-analysis. J Natl Cancer Inst, August 2, 2006; 98(15): 1078 - 1087. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
L. E Kelemen, J. R Cerhan, U. Lim, S. Davis, W. Cozen, M. Schenk, J. Colt, P. Hartge, and M. H Ward Vegetables, fruit, and antioxidant-related nutrients and risk of non-Hodgkin lymphoma: a National Cancer Institute-Surveillance, Epidemiology, and End Results population-based case-control study Am. J. Clinical Nutrition, June 1, 2006; 83(6): 1401 - 1410. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 A. Kubo and D. A. Corley Body Mass Index and Adenocarcinomas of the Esophagus or Gastric Cardia: A Systematic Review and Meta-analysis. Cancer Epidemiol. Biomarkers Prev., May 1, 2006; 15(5): 872 - 878. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
X. Gao, P. E. Wilde, A. H. Lichtenstein, and K. L. Tucker The 2005 USDA Food Guide Pyramid Is Associated with More Adequate Nutrient Intakes within Energy Constraints than the 1992 Pyramid J. Nutr., May 1, 2006; 136(5): 1341 - 1346. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
C. A. Gonzalez, P. Jakszyn, G. Pera, A. Agudo, S. Bingham, D. Palli, P. Ferrari, H. Boeing, G. del Giudice, M. Plebani, et al. Meat intake and risk of stomach and esophageal adenocarcinoma within the European Prospective Investigation Into Cancer and Nutrition (EPIC). J Natl Cancer Inst, March 1, 2006; 98(5): 345 - 354. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
A. R. Kristal, P. L. Blount, J. M. Schenk, C. A. Sanchez, P. S. Rabinovitch, R. D. Odze, J. Standley, T. L. Vaughan, and B. J. Reid Low-Fat, High Fruit and Vegetable Diets and Weight Loss Do Not Affect Biomarkers of Cellular Proliferation in Barrett Esophagus Cancer Epidemiol. Biomarkers Prev., October 1, 2005; 14(10): 2377 - 2383. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 D M Clements, D A Oleesky, S C Smith, H Wheatley, D A Hullin, T J Havard, and D J Bowrey A study to determine plasma antioxidant concentrations in patients with Barrett's oesophagus J. Clin. Pathol., May 1, 2005; 58(5): 490 - 492. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
J. R. Olliver, L. J. Hardie, Y. Gong, S. Dexter, D. Chalmers, K. M. Harris, and C. P. Wild Risk Factors, DNA Damage, and Disease Progression in Barrett's Esophagus Cancer Epidemiol. Biomarkers Prev., March 1, 2005; 14(3): 620 - 625. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 E. Cheong, K. Ivory, J. Doleman, M.L. Parker, M. Rhodes, and I.T. Johnson Synthetic and naturally occurring COX-2 inhibitors suppress proliferation in a human oesophageal adenocarcinoma cell line (OE33) by inducing apoptosis and cell cycle arrest Carcinogenesis, October 1, 2004; 25(10): 1945 - 1952. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 W J Lee, W Lijinsky, E F Heineman, R S Markin, D D Weisenburger, and M H Ward Agricultural pesticide use and adenocarcinomas of the stomach and oesophagus Occup. Environ. Med., September 1, 2004; 61(9): 743 - 749. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
F. Levi, C. Pasche, F. Lucchini, C. Bosetti, and C. La Vecchia Processed meat and the risk of selected digestive tract and laryngeal neoplasms in Switzerland Ann. Onc., February 1, 2004; 15(2): 346 - 349. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
X. Gao, M. Yao, M. A. McCrory, G. Ma, Y. Li, S. B. Roberts, and K. L. Tucker Dietary Pattern Is Associated with Homocysteine and B Vitamin Status in an Urban Chinese Population J. Nutr., November 1, 2003; 133(11): 3636 - 3642. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
H. Lin, O. I. Bermudez, and K. L. Tucker Dietary Patterns of Hispanic Elders Are Associated with Acculturation and Obesity J. Nutr., November 1, 2003; 133(11): 3651 - 3657. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
L. S. Engel, W.-H. Chow, T. L. Vaughan, M. D. Gammon, H. A. Risch, J. L. Stanford, J. B. Schoenberg, S. T. Mayne, R. Dubrow, H. Rotterdam, et al. Population Attributable Risks of Esophageal and Gastric Cancers J Natl Cancer Inst, September 17, 2003; 95(18): 1404 - 1413. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
K. L Erickson Dietary pattern analysis: a different approach to analyzing an old problem, cancer of the esophagus and stomach Am. J. Clinical Nutrition, January 1, 2002; 75(1): 5 - 7. [Full Text] [PDF]
|
|
| HOME | HELP | FEEDBACK | SUBSCRIPTIONS | ARCHIVE | SEARCH | TABLE OF CONTENTS |
