| HOME | HELP | FEEDBACK | SUBSCRIPTIONS | ARCHIVE | SEARCH | TABLE OF CONTENTS |
|
|
|
|||||||
|
|||||||||
Original Research Communication |
1 From the Unité Maladies Métaboliques et Micronutriments, INRA, Clermont-Ferrand/Theix, Saint-Genès-Champanelle, France (VT, NC, PG, VA-B, and PB); the Station de Technologie des Produits Végétaux, INRA Domaine St Paul, Avignon, France (CC-V and M-JA); and the Laboratoire de Nutrition Humaine, CRNH d'Auvergne, Clermont-Ferrand, France (CB).
Background: The results of epidemiologic studies have consistently shown associations between dietary intake or plasma carotenoid status and incidence of cancers and cardiovascular and eye diseases.
Objective: The aim was to assess whether vegetable-borne carotenoids (lycopene, lutein, and ß-carotene) compete for intestinal absorption and whether this affects the plasma status of carotenoids in the medium term (ie, after 3 wk).
Design: During 3-wk periods separated by 3-wk washout periods, 20 women were supplemented with either 96 g tomato purée/d (14.98 mg lycopene + 1.50 mg ß-carotene), 92 g cooked chopped spinach/d (11.93 mg lutein + 7.96 mg ß-carotene), 96 g tomato purée/d + 92 g chopped spinach/d, 96 g tomato purée/d + 2 lutein pills (12 mg lutein), or 92 g chopped spinach/d + 1 lycopene pill (15 mg lycopene). Plasma carotenoids were measured before and after each supplementation period. The subjects also participated in postprandial experiments in which they ingested meals containing double amounts of the supplements described above. Carotenoids were measured in chylomicrons to assess the interaction of carotenoids on absorption.
Results: Adding a second carotenoid to a meal that provided a first carotenoid diminished the chylomicron response to the first carotenoid. However, cosupplementation with a second carotenoid of a diet supplemented with a first carotenoid did not diminish the medium-term plasma response to the first carotenoid.
Conclusion: Consumption of carotenoids from different vegetable sources does not diminish plasma carotenoid concentrations in the medium term, despite the finding in postprandial testing of competitive inhibitory interactions among different carotenoids.
Key Words: Carotenoids • bioavailability • spinach • tomatoes • antioxidants • women • ß-carotene • lycopene • lutein • France
This article has been cited by other articles:
|
|
 |
|
  J. P. Mills, P. W. Simon, and S. A. Tanumihardjo Biofortified Carrot Intake Enhances Liver Antioxidant Capacity and Vitamin A Status in Mongolian Gerbils J. Nutr., September 1, 2008; 138(9): 1692 - 1698. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
P. Borel, M. Moussa, E. Reboul, B. Lyan, C. Defoort, S. Vincent-Baudry, M. Maillot, M. Gastaldi, M. Darmon, H. Portugal, et al. Human Plasma Levels of Vitamin E and Carotenoids Are Associated with Genetic Polymorphisms in Genes Involved in Lipid Metabolism J. Nutr., December 1, 2007; 137(12): 2653 - 2659. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
J. P. Mills, P. W. Simon, and S. A. Tanumihardjo {beta}-Carotene from Red Carrot Maintains Vitamin A Status, but Lycopene Bioavailability Is Lower Relative to Tomato Paste in Mongolian Gerbils J. Nutr., June 1, 2007; 137(6): 1395 - 1400. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 K. L Molldrem, J. Li, P. W Simon, and S. A Tanumihardjo Lutein and {beta}-carotene from lutein-containing yellow carrots are bioavailable in humans Am. J. Clinical Nutrition, July 1, 2004; 80(1): 131 - 136. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 J. A. Mares, T. L. La Rowe, and B. A. Blodi Doctor, What Vitamins Should I Take for My Eyes? Arch Ophthalmol, April 1, 2004; 122(4): 628 - 635. [Full Text] [PDF]
|
|
|
|
 |
|
 V. Tyssandier, E. Reboul, J.-F. Dumas, C. Bouteloup-Demange, M. Armand, J. Marcand, M. Sallas, and P. Borel Processing of vegetable-borne carotenoids in the human stomach and duodenum Am J Physiol Gastrointest Liver Physiol, June 1, 2003; 284(6): G913 - G923. [Abstract] [Full Text] [PDF]
|
|
| HOME | HELP | FEEDBACK | SUBSCRIPTIONS | ARCHIVE | SEARCH | TABLE OF CONTENTS |
