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American Journal of Clinical Nutrition, Vol. 75, No. 5, 872-879, May 2002
© 2002 American Society for Clinical Nutrition


Original Research Communication

Plasma ß-carotene and retinol concentrations of children increase after a 30-d supplementation with the fruit Momordica cochinchinensis (gac)1,2,3

Le T Vuong, Stephen R Dueker and Suzanne P Murphy

1 From the Department of Nutrition, University of California, Davis (LTV and SRD), and the Cancer Research Center of Hawaii, University of Hawaii, Honolulu (SPM).

Background: In rural Vietnam, vitamin A deficiency is a concern. Among the indigenous fruit and vegetables, Momordica cochinchinensis (gac) fruit has been identified as having the highest ß-carotene concentration. Locally, it is mixed with rice in a preparation called xoi gac.

Objective: The purpose of this study was to assess this ß-carotene– rich rice preparation as a source of provitamin A for children in rural Vietnam.

Design: Preschoolers (n = 185) participated in a 30-d controlled supplementation trial. Children with low hemoglobin concentrations were assigned to 1 of 3 groups: a fruit group, who received xoi gac that contained 3.5 mg ß-carotene per serving; a powder group, who received rice mixed with 5.0 mg synthetic ß-carotene powder; and a control group, who received rice without fortification.

Results: The mean increase in plasma ß-carotene concentrations in the fruit and powder groups was significantly greater than that in the control group (P < 0.0001). After supplementation, the mean plasma retinol concentration in the fruit group was significantly higher than that in the control (P = 0.006) and powder (P = 0.0053) groups. Among the children with initial hemoglobin concentrations <=110 g/L, the mean increase in hemoglobin concentrations in the fruit group was marginally higher than that in the control group (P = 0.017) but was not significantly different from that in the powder group.

Conclusions: ß-Carotene from xoi gac is a good source of provitamin A carotenoids. Severely anemic children might particularly benefit from routine xoi gac consumption

Key Words: ß-Carotene • carotene-rich food • lycopene • retinol • preschoolers • vitamin A • vitamin A deficiency • food-based approach • ß-carotene supplementation • Momordica cochinchinensisxoi gac • Vietnam




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