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American Journal of Clinical Nutrition, Vol. 76, No. 1, 290S-298S, July 2002
© 2002 American Society for Clinical Nutrition


Supplements

Glycemic index and disease1,2,3,4

F Xavier Pi-Sunyer

1 From the Obesity Research Center, St Luke's–Roosevelt Hospital Center, Columbia University College of Physicians and Surgeons, New York.

It has been suggested that foods with a high glycemic index are detrimental to health and that healthy people should be told to avoid these foods. This paper takes the position that not enough valid scientific data are available to launch a public health campaign to disseminate such a recommendation. This paper explores the glycemic index and its validity and discusses the effect of postprandial glucose and insulin responses on food intake, obesity, type 1 diabetes, and cardiovascular disease. Presented herein are the reasons why it is premature to recommend that the general population avoid foods with a high glycemic index.

Key Words: Glycemic index • glucose • insulin • obesity • diabetes • cardiovascular disease




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