| HOME | HELP | FEEDBACK | SUBSCRIPTIONS | ARCHIVE | SEARCH | TABLE OF CONTENTS |
|
|
|
|||||||
|
|||||||||
Original Research Communication |
1 From the Pennington Biomedical Research Center, Louisiana State University, Baton Rouge.
Background: Nuts appear to have cardiovascular benefits but their effect in diabetic patients is unclear.
Objective: The objective was to assess effects of almond-enriched diets on insulin sensitivity and lipids in patients with normoglycemia or type 2 diabetes.
Design: Study 1 assessed the effect of almonds on insulin sensitivity in 20 free-living healthy volunteers who received 100 g almonds/d for 4 wk. Study 2 was a randomized crossover study that compared 4 diets in 30 volunteers with type 2 diabetes: 1) high-fat, high-almond (HFA; 37% total fat, 10% from almonds); 2) low-fat, high-almond (LFA; 25% total fat, 10% from almonds); 3) high-fat control (HFC; 37% total fat, 10% from olive or canola oil); and 4) low-fat control (LFC; 25% total fat, 10% from olive or canola oil). After each 4-wk diet, serum lipids and oral glucose tolerance were measured.
Results: In study 1, almond consumption did not change insulin sensitivity significantly, although body weight increased and total and LDL cholesterol decreased by 21% and 29%, respectively (P < 0.05). In study 2, total cholesterol was lowest with the HFA diet (4.46 ± 0.14, 4.52 ± 0.14, 4.63 ± 0.14, and 4.63 ± 0.14 mmol/L with the HFA, HFC, LFA, and LFC diets, respectively; P = 0.0004 for fat level). HDL cholesterol was significantly lower with the almond diets (P = 0.002); however, no significant effect of fat source on LDL:HDL was observed. Glycemia was unaffected.
Conclusions: Almond-enriched diets do not alter insulin sensitivity in healthy adults or glycemia in patients with diabetes. Almonds had beneficial effects on serum lipids in healthy adults and produced changes similar to high monounsaturated fat oils in diabetic patients.
Key Words: Nuts • almonds • insulin resistance • type 2 diabetes • lipoproteins • glucose tolerance
This article has been cited by other articles:
|
|
 |
|
  R. D. Mattes, P. M. Kris-Etherton, and G. D. Foster Impact of Peanuts and Tree Nuts on Body Weight and Healthy Weight Loss in Adults J. Nutr., September 1, 2008; 138(9): 1741S - 1745S. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
P. M. Kris-Etherton, F. B. Hu, E. Ros, and J. Sabate The Role of Tree Nuts and Peanuts in the Prevention of Coronary Heart Disease: Multiple Potential Mechanisms J. Nutr., September 1, 2008; 138(9): 1746S - 1751S. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
D. J. A. Jenkins, F. B. Hu, L. C. Tapsell, A. R. Josse, and C. W. C. Kendall Possible Benefit of Nuts in Type 2 Diabetes J. Nutr., September 1, 2008; 138(9): 1752S - 1756S. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 M. J. Sheridan, J. N. Cooper, M. Erario, and C. E. Cheifetz Pistachio Nut Consumption and Serum Lipid Levels J. Am. Coll. Nutr., April 1, 2007; 26(2): 141 - 148. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
J. Mukuddem-Petersen, W. Oosthuizen, and J. C. Jerling A Systematic Review of the Effects of Nuts on Blood Lipid Profiles in Humans J. Nutr., September 1, 2005; 135(9): 2082 - 2089. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 A.-M. Paradis, B. Fontaine-Bisson, Y. Bosse, J. Robitaille, S. Lemieux, H. Jacques, B. Lamarche, A. Tchernof, P. Couture, and M.-C. Vohl The peroxisome proliferator-activated receptor {alpha} Leu162Val polymorphism influences the metabolic response to a dietary intervention altering fatty acid proportions in healthy men Am. J. Clinical Nutrition, February 1, 2005; 81(2): 523 - 530. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
M.-P. St-Onge Dietary fats, teas, dairy, and nuts: potential functional foods for weight control? Am. J. Clinical Nutrition, January 1, 2005; 81(1): 7 - 15. [Abstract] [Full Text] [PDF]
|
|
| HOME | HELP | FEEDBACK | SUBSCRIPTIONS | ARCHIVE | SEARCH | TABLE OF CONTENTS |
