| HOME | HELP | FEEDBACK | SUBSCRIPTIONS | ARCHIVE | SEARCH | TABLE OF CONTENTS |
|
|
|
|||||||
|
|||||||||
ORIGINAL RESEARCH COMMUNICATION |
1 From the Departments of Dietetics (PLMC-R), Clinical Chemistry (BVK), and Surgery (PBS), University Hospital Maastricht, Maastricht, Netherlands.
Background: Bioelectrical impedance spectroscopy (BIS) may be of value in identifying patients with nutritional depletion.
Objective: The primary aim of the study was to assess the validity of BIS in patients with gastrointestinal disease. The secondary aim was to compare different screening methods for identifying nutritionally depleted patients.
Design: In 70 patients with gastrointestinal disease, BIS measurements were performed and fluid compartments were calculated from extrapolated resistance (R) values of extracellular (RECW) and intracellular (RICW) water based on mixture equations. Results were compared with total body water and ECW, which were measured by dilution methods. Patients were classified as depleted if their actual fat-free mass (FFM) was <90% of their ideal FFM (iFFM). Different screening approaches for depletion were compared: the impedance vector method and the resistance index (RI) in relation to iFFM (RI/iFFM).
Results: Total body water and ICW were largely underestimated (4 L) in the not-depleted patients but not in the depleted patients. In both groups, ECW was slightly overestimated (0.6–0.7 L). The critical frequency was 60% higher and the membrane capacitance was 40% lower in the depleted than in the not-depleted patients. The impedance vector method failed to identify depleted patients, whereas the proposed ratio at R50 (R measured at 50 kHz) and Rinf (R at infinite frequency) resulted in comparable sensitivity (86%) and specificity (73–80%).
Conclusions: BIS measures of body fluids are influenced by the presence of depletion, probably because of alterations in the electric properties of the body at the cellular level. However, for screening purposes, the use of the ratio (L2/R)/iFFM at R50 and Rinf may be of value.
Key Words: Patients • gastrointestinal disease • depletion • body composition • bioelectrical impedance spectroscopy • BIS • total body water • extracellular water • intracellular water • screening
This article has been cited by other articles:
|
|
 |
|
  J. S. Powers, L. Choi, R. Bitting, N. Gupta, and M. Buchowski Rapid Measurement of Total Body Water to Facilitate Clinical Decision Making in Hospitalized Elderly Patients J Gerontol A Biol Sci Med Sci, June 1, 2009; 64A(6): 664 - 669. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 C. Earthman, D. Traughber, J. Dobratz, and W. Howell Bioimpedance Spectroscopy for Clinical Assessment of Fluid Distribution and Body Cell Mass Nutr Clin Pract, August 1, 2007; 22(4): 389 - 405. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 G. Sun, C. R French, G. R Martin, B. Younghusband, R. C Green, Y.-g. Xie, M. Mathews, J. R Barron, D. G Fitzpatrick, W. Gulliver, et al. Comparison of multifrequency bioelectrical impedance analysis with dual-energy X-ray absorptiometry for assessment of percentage body fat in a large, healthy population Am. J. Clinical Nutrition, January 1, 2005; 81(1): 74 - 78. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
D. Gupta, C. A Lammersfeld, J. L Burrows, S. L Dahlk, P. G Vashi, J. F Grutsch, S. Hoffman, and C. G Lis Bioelectrical impedance phase angle in clinical practice: implications for prognosis in advanced colorectal cancer Am. J. Clinical Nutrition, December 1, 2004; 80(6): 1634 - 1638. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
A. C. Buchholz, C. Bartok, and D. A. Schoeller The Validity of Bioelectrical Impedance Models in Clinical Populations Nutr Clin Pract, October 1, 2004; 19(5): 433 - 446. [Abstract] [Full Text] [PDF]
|
|
| HOME | HELP | FEEDBACK | SUBSCRIPTIONS | ARCHIVE | SEARCH | TABLE OF CONTENTS |
