AJCN Tufts Nutrition Symposium, Boston Sept 24-26
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American Journal of Clinical Nutrition, Vol 8, 434-444, Copyright © 1960 by The American Society for Clinical Nutrition, Inc.

Vitamin B6, Serum Lipids and Placental Arteriolar Lesions in Human Pregnancy

A Preliminary Report

JOSEPH R. SWARTWOUT M.D.1, WALTER G. UNGLAUB M.D.1, and ROBERT CRAFT SMITH M.D.1

1 From the Department of Obstetrics and Gynecology, and the Nutrition and Metabolism Research Laboratories, Department of Medicine, and the Department of Pathology, Tulane University School of Medicine and the Charity Hospital of Louisiana, New Orleans, Louisiana

A preliminary report is given on a study of the effects of sufficiency or deficiency of vitamin B6 on placental vessels and serum lipids in human pregnancy. The women given a placebo had a high xanthurenic acid output throughout pregnancy and had more placental arteriolar changes than the group receiving supplements of pyridoxine. The two groups are too small for the vascular differences to be statistically significant. However, there was a significant difference in fetal and placental weight, with the group not receiving supplements having heavier babies and placentas. The serum lipid values were not different in the two groups, and both groups showed a high gradient across the placenta for cholesterol.






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Copyright © 1960 by The American Society for Nutrition